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ICU CONNECT: Study Comparing EMG in Healthy Volunteers and ICU Patients.

Endeavor Health · NCT07699562

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 18–90 · All sexes
Healthy volunteers
Accepted
Study type
Interventional · Not applicable
Target enrollment
24
US sites recruiting
1
Study start
June 2026
Record last updated
July 13, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

This study is testing whether a non-invasive nerve monitoring device (TetraGraph) can accurately detect early signs of ICU-acquired weakness by comparing readings from the device with standard nerve conduction/EMG tests done by a specialist to see if they match. They will focus on muscle response signals in the hand and leg over about 10 days in three groups: healthy volunteers, ICU patients who are not on ventilators, and ICU patients who are on ventilators.

Being studied: TetraGraph; Electromyography; Nerve conduction studies

Conditions: ICU Acquired Weakness

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • Cohort 1: Healthy volunteers

Inclusion criteria

  • Subjects must be > 18 years old and \< 90 years old.
  • Subjects must consent to participate. Cohort 2: Non-intubated critically ill patients

Inclusion criteria

  • Subjects may be male or female.
  • Subjects must be > 18 years old and \< 90 years old.
  • Subjects must have a POA or next of kin who is able to consent (for those in the ICU and who are unable to consent themselves).

Cohort 3: Intubated critically ill patients

Inclusion criteria

  • Subjects may be male or female.
  • Subjects must be > 18 years old and \< 90 years old.
  • Subjects must have a POA or next of kin who is able to consent (for those in the ICU and who are unable to consent themselves).
  • For the Subjects in the ICU that are intubated, they must be planned to be intubated for at least 24 hours.
  • Subjects must be intubated for no longer than ≥ 72 hours before enrollment.

Exclusion Criteria

  • Cohort 1: Healthy volunteers

Exclusion criteria

  • Subjects with previous paralysis or neuromuscular disease.
  • Subjects with spinal cord or brain injuries that impact motor function.
  • Subjects with an allergy to clinical adhesive or hydrogel. Cohort 2: Non-intubated critically ill patients

Exclusion criteria

  • Subjects with previous paralysis or neuromuscular diseases.
  • Subjects with previous peripheral nerve injuries to the tested limbs.
  • Subjects with spinal cord or brain injuries (including stroke) that impact motor function.
  • Subjects without a POA or next of kin for those patients that are unable to consent themselves.
  • Subjects with an allergy to clinical adhesive or hydrogel. Cohort 3: Intubated critically ill patients

Exclusion criteria

  • Subjects with previous paralysis or neuromuscular disease
  • Subjects with previous peripheral nerve injuries to the tested limbs.
  • Subjects with spinal cord or brain injuries that impact motor function.
  • Subjects without a POA or next of kin for those patients that are in the intubated arm.
  • Subjects with intubations expected to last less than 24 hours.
  • Subjects who have already been intubated for > 72 hours.
  • Subjects with an allergy to clinical adhesive or hydrogel.

Recruiting US locations

  • Endeavor Health

    Evanston, IL 60201

    Site contact: Jessica Brickner · 847-570-1197 · jessica.brickner@endeavorhealth.org

Study contacts (from the official record)

  • Jessica Brickner · 847-570-1197 · jessica.brickner@endeavorhealth.org
  • Nia Moragne · 847-570-1197 · nia.moragne@endeavorhealth.org
All healthy volunteers studies in Illinois →
ICU CONNECT: Study Comparing EMG in Healthy Volunteers and ICU… (NCT07699562) | Bored Studies