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Identifying and Characterizing Preclinical MS

Yale University · with Roche-Genentech · NCT05787795

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 18+ · All sexes
Healthy volunteers
Accepted
Study type
Observational
Target enrollment
1000
US sites recruiting
1
Study start
June 21, 2022
Record last updated
August 27, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

The purpose of this research study is to try and identify risk factors and biologic changes that suggest that someone may go on to develop multiple sclerosis before a person has shown any symptoms of the disease.

Being studied: biological samples

Conditions: Multiple Sclerosis

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • Age 18+
  • Having one or more risk factors for multiple sclerosis, including one or more of the below:
  • Individuals known to have a radiologically isolated syndrome
  • Individuals with a family history of multiple sclerosis (first degree family member)
  • Individuals with personal risk factors, which are known to include smoking, obesity, Epstein Barr virus infections, Vitamin D deficiency, genetic risk score

Exclusion Criteria

  • Currently pregnant
  • Diagnosis of multiple sclerosis or any ongoing, systemic autoimmune disease
  • Ongoing treatment with immunosuppressive medications

Recruiting US locations

  • Yale University

    North Haven, CT 06473

    Site contact: Cynthia Marques · 203-287-6100 · cynthia.marques@yale.edu

Study contacts (from the official record)

  • Erin Longbrake, MD · 860-287-6100 · erin.longbrake@yale.edu
All neurology studies in Connecticut →
Identifying and Characterizing Preclinical MS (NCT05787795) | Bored Studies