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Imaging Studies in Corticobasal Syndrome

Jennifer Whitwell · with National Institute on Aging (NIA) · NCT07000851

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 18+ · All sexes
Healthy volunteers
Accepted
Study type
Observational
Target enrollment
80
US sites recruiting
1
Study start
June 25, 2025
Record last updated
July 14, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

The primary goal of this study is to investigate inflammation and white matter damage in corticobasal syndrome and determine whether these processes are related to each other. The investigator's will address our goal by using neuroimaging and blood plasma biomarkers, as well as molecular pathology.

Being studied: C-11 ER176 Radiotracer; C-11 PiB; AV1451 Tau

Conditions: Cortico Basal Degeneration; Corticobasal Syndrome; Corticobasal Syndrome(CBS); Corticobasal Degeneration; Corticobasal Degeneration (CBD); Corticobasal Syndrome (CBS)

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • Age 18 years or older
  • Meet possible or probable CBS criteria

Exclusion Criteria

  • Subjects will be excluded if MRI is contraindicated (due to implanted device, severe claustrophobia, etc)
  • Subjects will be excluded if they have a concurrent illnesses or structural abnormality that could account for the CBS syndrome
  • Subjects will be excluded if they have a mutation in the progranulin gene
  • Subjects will excluded if they have received anti-Aβ therapy
  • Women who are pregnant will be excluded
  • Subjects will be excluded if they are actively taking daily anti-inflammatory medications (NSAIDs, corticosteriods, etc)
  • Subjects will be excluded if they have generalized inflammatory condition and treatment with immunosuppressive, corticoid/glucocorticoid, steroidal or non-steroidal anti-inflammatory medication within 2 weeks of scanning

Recruiting US locations

Study contacts (from the official record)

  • Megan J Meyer, M.B.A. · 507-293-1164 · meyer.megan6@mayo.edu
  • Sarah M Boland, CCRP · 507284-3863 · boland.sarah@mayo.edu
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Imaging Studies in Corticobasal Syndrome (NCT07000851) | Bored Studies