Immediate Versus Delayed Loading of Maxillary Overdenture Implants

Inclusion Criteria

• Males and females must be at least ≥ 21 years of age
• Fully edentulous maxilla
• The implant site has to be healed for at least 4 months after extraction
• Wearing complete dentures deemed adequate
• Orthopantomogram available (OPT)
• Adequate amount of bone at least at the 2nd premolar position to house at minimum a 3.5 x 10 mm BLX-Roxolid implant
• No bone grafting required
• Implant IT ≥ 20 N/cm

Exclusion Criteria

• Conditions requiring chronic routine prophylactic use of antibiotics
• Conditions requiring prolonged use of steroids
• History of leukocyte dysfunction and deficiencies
• Bleeding disorders
• History of neoplastic disease requiring use of radiation or chemotherapy
• Metabolic bone disorders
• Uncontrolled endocrine disorder
• Use of any investigational drug or device within the 30-day period prior to implant surgery
• Vaping, Tobacco Chewing or Smoking more than 10 cigarettes a day
• Alcoholism or drug abuse
• Patient infected with HIV
• Condition or circumstances, in the opinion of the investigator, which would prevent completion of study participation or interfere with analysis of study results, such as as history of non-compliance, unreliability.
• Local inflammation including untreated periodontitis
• Mucosal disease such as erosive lichen planus
• History of local irradiation therapy
• Osseous lesion
• Severe bruxism and clenching habits
• Active infection with suppuration or fistula track
• Persistent intraoral infection
• Lack of primary stability \<20Ncm. In this instance, the patient must be withdrawn and treated according to the standard protocol.
• Inadequate oral hygiene or unmotivated home care.
• Bone grafting needed
• Inadequate bone volume for implants insertion as measured on the pre-treatment cone beam computed tomography (CBCT).