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RecruitingAccepts healthy volunteers

Immune Function and the Progression to T1D

University of Florida · with Juvenile Diabetes Research Foundation, National Institute of Allergy and Infectious Diseases (NIAID) · NCT05899439

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 0 mo–100 · All sexes
Healthy volunteers
Accepted
Study type
Observational
Target enrollment
2800
US sites recruiting
3
Study start
January 1, 2005
Record last updated
April 9, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

To elucidate the mechanisms by which type 1 diabetes-associated genes; IFIH1, TYK2, IKZF4, as well as total genetic risk, impart functional immunoregulatory abnormalities that result in expansion of self-reactive adaptive immune cells, defective regulatory/effector mechanisms in T cells, inflammatory antigen presenting cells, and abnormal immune function in T cells and B cells.

Being studied: blood draw

Conditions: Type 1 Diabetes

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria: able to have blood drawn -

Exclusion Criteria: none

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Recruiting US locations

  • Kieran McGrail

    Gainesville, FL 32610

    Site contact: Kieran McGrail · 352-273-9299 · mcgrail@pathology.ufl.edu

  • The Ohio State University

    Columbus, OH 43210

    Site contact: Billur Akkaya, MD DPhil · 614-688-1187 · billur.akkaya@osumc.edu

  • Baylor College of Medicine, Center for Research Advancement - Texas Children's Hospital

    Houston, TX 77030

    Site contact: Maria Redondo, MD, PhD, MPH · 832-822-1019 · redondo@bcm.edu

Study contacts (from the official record)

  • Jennifer L Hosford, MPH · 352-294-5759 · jennifer.hosford@peds.ufl.edu
  • Kieran McGrail · (352) 273-9299 · mcgrail@pathology.ufl.edu
All diabetes studies in Florida →
Immune Function and the Progression to T1D (NCT05899439) | Bored Studies