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Impact of Yo-Yo Sleep on Cardiometabolic Health

Columbia University · with Icahn School of Medicine at Mount Sinai, University of Colorado, Denver · NCT05880758

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 18–49 · All sexes
Healthy volunteers
Accepted
Study type
Interventional · Not applicable
Target enrollment
72
US sites recruiting
1
Study start
September 22, 2023
Record last updated
May 18, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

The goal of this clinical trial is to test the impact of repeated intermittent short sleep, with short sleep maintained 5 days per week followed by 2 days of prolonged sleep, compared to daily adequate sleep, on energy balance and cardiometabolic risk. A secondary goal of this research is to determine if maintaining a constant midpoint of sleep while undergoing intermittent short sleep, leads to better outcomes than intermittent short sleep with a 2-hour delay in sleep midpoint. The aims of this research will be tested in the context of a 3-group, parallel-arm, outpatient intervention of 4 weeks in duration, in young-to-middle-aged adults (aged 18-49 years).

Being studied: Intermittent Short Sleep (ISS); Social Jetlag (SJL); Sustained Adequate Sleep (SAS)

Conditions: Cardiometabolic Syndrome; Obesity

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • Aged 18 to 49 years
  • BMI 20-29.9 kg/m2
  • Habitually sleeping 7-9 hours/night without sleep aids or naps

Exclusion Criteria

  • Sleep disorders
  • Psychiatric disorders (including eating disorders) and seasonal affective disorder
  • Pregnancy (current/prior year)
  • Breastfeeding
  • Smokers (Any cigarette smoking or ex-smokers \<3years)
  • Diabetes
  • Elevated blood pressure, taking beta-blockers
  • Individuals taking anti-coagulants or anti-platelets
  • Recent weight change or participation in a weight loss program or have ever had bariatric surgery or other weight loss or gastrointestinal procedure.
  • Travel across time zones; shift work (non-traditional hours)

Recruiting US locations

  • Columbia University Irving Medical Center

    New York, NY 10032

    Site contact: Marie-Pierre St-Onge, PhD · 212-305-9549 · ms2554@cumc.columbia.edu

Study contacts (from the official record)

  • Marie-Pierre St-Onge, PhD · 212-305-9549 · ms2554@cumc.columbia.edu
  • Greiby Mercedes · 646-761-3455 · gdm2130@cumc.columbia.edu
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Impact of Yo-Yo Sleep on Cardiometabolic Health (NCT05880758) | Bored Studies