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Individual Factors of CBT Underlying Success

University of Washington · with National Institute of Mental Health (NIMH) · NCT06678295

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 18–45 · All sexes
Healthy volunteers
Accepted
Study type
Interventional · Not applicable
Target enrollment
160
US sites recruiting
1
Study start
October 15, 2024
Record last updated
February 17, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

The purpose of this study is to understand why some individuals respond fully to cognitive behavioral therapy and others do not, based on multiple sources of data such as neural, neurocognitive, clinical, and self-report data.

Being studied: Cognitive Behavioral Therapy

Conditions: Social Anxiety Disorder; Body Dysmorphic Disorder

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

Clinical sample (N=110):

  • Men and women, age 18-45
  • Treatment-seeking individuals who meet criteria for a primary DSM-5 diagnosis of primary social anxiety disorder (SAD) or body dysmorphic disorder (BDD) based on the SCID-5-RV
  • Fluent in English and willing to provide informed consent.

Control sample (N=50):

  • Men and women, age 18-45
  • No current or lifetime history of psychiatric disorders, as assessed using the SCID-5-RV
  • Meet criteria for low levels of anxiety (GAD-7 score of \<8) and depression (PHQ-9 score \<10)
  • Fluent in English and willing to provide informed consent

Exclusion Criteria

All groups

  • Score \< 80 based on WRAT5 Word Reading Subtest
  • fMRI contraindications (e.g., electronic medical devices such as pacemakers, implanted defibrillators, etc.; metal implants not approved for MRI; pregnancy; claustrophobia)
  • Active suicidal or homicidal ideation, or any features requiring a higher level of care 3. Lifetime history of manic or hypomanic episode, psychotic symptoms, traumatic brain injury, neurological disorder, pervasive developmental disorder, or attention deficit-hyperactivity disorder; active alcohol or substance use disorder in the past 6 months 4. Current use of psychotropic medications, except antidepressants taken at a stable dose for 3 months prior to study baseline 5. Previous CBT non-responder or current CBT

Recruiting US locations

  • University of Washington

    Seattle, WA 98105

    Site contact: Randhara Kotuwelle, B.A. · 206-221-1278 · ifocuscbt@uw.edu

Study contacts (from the official record)

  • Angela Fang, PhD · (206) 616-5783 · angfang@uw.edu
All mental health studies in Washington →
Individual Factors of CBT Underlying Success (NCT06678295) | Bored Studies