Individual Factors of CBT Underlying Success
University of Washington · with National Institute of Mental Health (NIMH) · NCT06678295
Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.
Key facts
- Compensation
- Not posted. Ask the study team before screening.
- Who can join
- Ages 18–45 · All sexes
- Healthy volunteers
- Accepted
- Study type
- Interventional · Not applicable
- Target enrollment
- 160
- US sites recruiting
- 1
- Study start
- October 15, 2024
- Record last updated
- February 17, 2026
Status re-checked against ClinicalTrials.gov within the last 12 hours.
What the study is about
The purpose of this study is to understand why some individuals respond fully to cognitive behavioral therapy and others do not, based on multiple sources of data such as neural, neurocognitive, clinical, and self-report data.
Being studied: Cognitive Behavioral Therapy
Conditions: Social Anxiety Disorder; Body Dysmorphic Disorder
Eligibility criteria
Copied from the official record. The study team makes the final decision at screening.
Show full criteria
Inclusion Criteria
Clinical sample (N=110):
- Men and women, age 18-45
- Treatment-seeking individuals who meet criteria for a primary DSM-5 diagnosis of primary social anxiety disorder (SAD) or body dysmorphic disorder (BDD) based on the SCID-5-RV
- Fluent in English and willing to provide informed consent.
Control sample (N=50):
- Men and women, age 18-45
- No current or lifetime history of psychiatric disorders, as assessed using the SCID-5-RV
- Meet criteria for low levels of anxiety (GAD-7 score of \<8) and depression (PHQ-9 score \<10)
- Fluent in English and willing to provide informed consent
Exclusion Criteria
All groups
- Score \< 80 based on WRAT5 Word Reading Subtest
- fMRI contraindications (e.g., electronic medical devices such as pacemakers, implanted defibrillators, etc.; metal implants not approved for MRI; pregnancy; claustrophobia)
- Active suicidal or homicidal ideation, or any features requiring a higher level of care 3. Lifetime history of manic or hypomanic episode, psychotic symptoms, traumatic brain injury, neurological disorder, pervasive developmental disorder, or attention deficit-hyperactivity disorder; active alcohol or substance use disorder in the past 6 months 4. Current use of psychotropic medications, except antidepressants taken at a stable dose for 3 months prior to study baseline 5. Previous CBT non-responder or current CBT
Recruiting US locations
University of Washington
Seattle, WA 98105
Site contact: Randhara Kotuwelle, B.A. · 206-221-1278 · ifocuscbt@uw.edu
Study contacts (from the official record)
- Angela Fang, PhD · (206) 616-5783 · angfang@uw.edu
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