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Influence of the Gut Microbiome on Blueberry Polyphenol Metabolites

Colorado State University · with Florida State University, National Center for Complementary and Integrative Health (NCCIH) · NCT07607158

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 18+ · All sexes
Healthy volunteers
Accepted
Study type
Interventional · Not applicable
Target enrollment
125
US sites recruiting
1
Study start
January 27, 2026
Record last updated
May 26, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

The objective of this study is to determine whether inter-individual differences in the gut microbiome influence exposure to blueberry polyphenol metabolites. We will use pharmacokinetics of blueberry polyphenols after an acute blueberry exposure to group individuals into "metabotypes", groups of individuals based on similarity in their metabolite profiles. We will then use multi-omic approaches to determine whether the gut microbiome predicts an individual's metabotype.

Being studied: Freeze-dried blueberry powder beverage

Conditions: Microbiome Analysis; Metabolomics

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • Healthy adults ≥18 years of age
  • Able and willing to provide informed consent
  • Willing and able to adhere to all study procedures and visit requirements

Exclusion Criteria

  • Age \<18 years
  • Pregnant or breastfeeding
  • Presence of chronic diseases, including but not limited to cardiovascular disease, diabetes, cancer, kidney, liver, gastrointestinal, or pancreatic disease
  • Use of medications for chronic diseases that may interfere with study outcomes
  • Any condition known to negatively impact nutrient absorption (e.g., inflammatory bowel disease, celiac disease, gastroparesis)
  • Anemia (hemoglobin \<13.5 g/dL in men or \<12.0 g/dL in women)
  • Body mass index (BMI) ≤18.5 kg/m²
  • Use of antibiotics within the past 2 months
  • Recent blood draw within 1 week prior to study participation
  • Currently participating in another research study involving a diet or exercise intervention
  • Known allergy or contraindication to blueberry products or study procedures
  • Unwilling or unable to comply with study requirements

Recruiting US locations

  • Colorado State University; Food and Nutrition Clinical Research Laboratory; Gifford Building Room 216; 502 West Lake Street, Fort Collins, CO 80523

    Fort Collins, CO 80523

    Site contact: Jenny Whittington, MS · 970-310-6843 · ijwhitt@rams.colostate.edu

Study contacts (from the official record)

  • Tiffany Weir, PhD · (970) 491-4631 · tiffany.weir@colostate.edu
  • Jenny Whittington, MS · (970) 310-6843 · ijwhitt@rams.colostate.edu
All healthy volunteers studies in Colorado →
Influence of the Gut Microbiome on Blueberry Polyphenol Metabolites (NCT07607158) | Bored Studies