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Inspiring Seniors Towards Exercise Promotion to Protect Cognition

Emory University · with Alzheimer's Association, University of North Carolina, Greensboro · NCT06496425

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 65+ · All sexes
Healthy volunteers
Accepted
Study type
Interventional · Not applicable
Target enrollment
80
US sites recruiting
1
Study start
May 15, 2024
Record last updated
April 30, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

The goal of this clinical trial is to test the benefits of beat-accented music stimulation (BMS) for behavioral changes of physical activity (PA) in older adults with subjective memory complaints. Specific Aims are to determine (1) whether BMS beneficially influences PA behaviors and psychological responses to PA in older adults for 6 months, and (2) whether exercising with BMS differently influences physical and cognitive functioning as well as quality of life in older adults. To test the effects of BMS on PA, participants will be randomly assigned to an exercise intervention that either includes BMS or does not include BMS. Participants will attend a supervised group strength training (ST) (30 minutes per day) and aerobic exercise (AE) (30-50 minutes per day) session for 3 days per week for the first 2 months, 1 day per week for the next 2 months (while encouraging participants to independently perform both AE and ST on other days), and independently for the final 2 months (always with a goal of performing >150minutes per week AE and 3 days per week of ST for 30 minutes per day).

Being studied: Beat-accentuated, personalized music stimulation (BMS); Strength Training (ST); Aerobic exercise (AE)

Conditions: Alzheimer Disease; Physical Activity

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • Adults at least 65 years old.
  • Ambulatory/capable of walking without pain or the use of assisted walking devices.
  • Able to speak and read English.
  • Healthy enough to exercise at moderate intensity with or without medical clearance by a primary care physician.
  • Living in the community for the duration of the study.
  • Having a reliable means of transportation.
  • Having a safe place at home or a residential area (at least 6 feet by 6 feet of open space) for unsupervised exercise training.
  • Being low-active (\< 60 min/week of moderate-intensity aerobic exercise and no strength training for the last 3 months).
  • Having SCC, defined by the Cognitive Change Index (CCI) ≥ 15.

Exclusion Criteria

  • Concurrent diagnosis of neurological disorder (e.g., dementia, Parkinson's disease, multiple sclerosis, stroke, etc.).
  • Known exercise contraindications (uncontrolled hypertension, joint problems, diabetes, metabolic conditions etc.).
  • Current cancer treatment.
  • Stroke or neural impairment in the past 6 months.
  • Hip/knee/spinal fracture or surgery in the past 6 months.
  • Unable or unwilling to attend intervention classes.
  • Currently participating in any other physical activity or fitness-related research study.
  • Use of medication for cognitive impairment.
  • Regularly drink > 14 alcoholic beverages a week or current illicit drug use.
  • Meet the threshold for cognitive impairment.
  • Meet the threshold for clinical depression.
  • Uncorrected hearing or visual impairments.
  • Unable to understand the study procedures.
  • One of the household members is participating in this study.

Recruiting US locations

  • Emory University

    Atlanta, GA 30324

    Site contact: Study Team · 404-727-8919 · istep@emory.edu

Study contacts (from the official record)

  • Study Team · 404-727-8919 · istep@emory.edu
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Inspiring Seniors Towards Exercise Promotion to Protect Cognition (NCT06496425) | Bored Studies