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Investigating the Link Between Type 2 Immunity and NAFLD in Human Obesity

Mayo Clinic · NCT04232566

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 30–70 · All sexes
Healthy volunteers
Accepted
Study type
Observational
Target enrollment
60
US sites recruiting
1
Study start
February 20, 2022
Record last updated
January 28, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

This study is being done to better understand the relationship between inflammation in adipose tissue (AT), abnormal deposition of fat around the liver and how this affects its appearance and function and ultimately insulin resistance.

Being studied: Bariatric surgery

Conditions: Obesity, Morbid; NASH - Nonalcoholic Steatohepatitis; Chronic Inflammation

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • Undergoing gastric bypass surgery
  • Confirmed AUROC F=0 or F>2 liver fibrosis
  • Age 30-70 years
  • BMI greater than 40 kg/m2
  • Negative pregnancy test (female only)
  • Lab Values: Normal TSH

Exclusion Criteria

  • Autoimmune diseases
  • Hepatitis B or C positive
  • Heavy alcohol use
  • Active smoking history
  • Active cancer history
  • History of asthma
  • History of COPD
  • Taking Plavix or Coumadin
  • Blood donation within past 2 months
  • Glucocorticoid Therapy
  • Taking antihistamine on regular basis

Recruiting US locations

  • Mayo Clinic in Arizona

    Scottsdale, AZ 85259

    Site contact: Stewart Keegan · 480-301-4164 · stewart.keegan@mayo.edu

Study contacts (from the official record)

  • Keegan M Stewart · 480-301-4164 · stewart.keegan@mayo.edu
All weight loss studies in Arizona →
Investigating the Link Between Type 2 Immunity and NAFLD in Human… (NCT04232566) | Bored Studies