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Investigational Use of Neuromuscular Ultrasound

National Institute of Neurological Disorders and Stroke (NINDS) · NCT05237973

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 18–110 · All sexes
Healthy volunteers
Accepted
Study type
Observational
Target enrollment
150
US sites recruiting
1
Study start
April 18, 2022
Record last updated
September 17, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

Background

Current techniques used to measure the health and function of a person s nerves and muscles are generally effective, but they do have limits. Researchers are looking for ways to improve the ability to observe nerves and muscles and how they function in this natural history protocol.

Objective

To study the use of ultrasound (sound waves) to learn more about nerves and muscles.

Eligibility

Healthy adults, aged 18 and older, with no history of stroke, nerve or muscular disorders, or spine surgery are also needed. A smaller population of adults aged 18 and older who have a neuromuscular disorder or show symptoms of nerve or muscle disorder will also be evaluated.

Design

Participants will be screened with a medical record review.

Participants will have up to 5 outpatient clinic visits. Most participants will have 1 or 2 visits. Visits will last for less than 3-4 hours each.

During each visit, participants will give a brief medical history and have a physical exam.

Participants will have ultrasounds to get pictures and measurements of their nerves and muscles. Gel will be applied to their skin. A probe will be placed on the skin surface. Sound waves sent through the probe will be used to create pictures.

Participants may have nerve conduction studies. Wires will be taped to the skin surface near a muscle or nerve in the arm or leg. The nerve will be stimulated with a small electric current that feels like a rubber band flick. The response will be recorded through the wires.

Conditions: Muscular Dystrophy; Peripheral Neuropathy; Motor Neuron Disorder; Normal Physiology

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria
  • INCLUSION CRITERIA:

In order to be eligible to participate in this study, an individual must meet all of the following criteria:

  • Healthy Volunteers-Adults
  • Healthy adults, male or female, aged 18 years old or older,
  • In good general health as evidenced by medical history, medical conditions under control such as hypertension acceptable.
  • Stated willingness to comply with all study procedures and availability for the duration of the study.
  • Ability of subject to understand and the willingness to sign a written informed consent document.
  • Participants with neuromuscular disorders
  • Adults, male or female, aged 18 years old or older,
  • Diagnosed with a neuromuscular disorder or have signs and symptoms of nerve or muscle disorder or neuromuscular diaphragm dysfunction.
  • Stated willingness to comply with all study procedures and availability for the duration of the study.
  • Ability of subject to understand and the willingness to sign a written informed consent document.

EXCLUSION CRITERIA

  • Healthy Volunteers-Adults

History of stroke, muscle disorders, peripheral neuropathy, or spine surgery

  • Participants with neuromuscular disorders

No clinical evidence of a neuromuscular disorder on clinical evaluation.

Recruiting US locations

  • National Institutes of Health Clinical Center

    Bethesda, MD 20892

    Site contact: For more information at the NIH Clinical Center contact Office of Patient Recruitment (OPR) · 800-411-1222 · ccopr@nih.gov

Study contacts (from the official record)

  • Candida C Silva · (301) 496-7428 · candida.silva@nih.gov
  • Tanya J Lehky, M.D. · (301) 496-7428 · lehkyt@ninds.nih.gov
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Investigational Use of Neuromuscular Ultrasound (NCT05237973) | Bored Studies