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Investigations of Dementia in Parkinson Disease

Washington University School of Medicine · with National Institutes of Health (NIH), National Institute of Neurological Disorders and Stroke (NINDS) · NCT02763683

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 50+ · All sexes
Healthy volunteers
Accepted
Study type
Observational
Target enrollment
320
US sites recruiting
1
Study start
June 2016
Record last updated
May 8, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

The purpose of this study is to use a brain imaging method called Pittsburgh B (PIB) Positron Emission Tomography (PET) and Vesicular Cholinergic Transport (VAT) PET to determine dementia subtypes in patients with Parkinson disease (PD). The ultimate goal of this project is to be able to identify individuals with PD who are at risk of developing dementia, and to distinguish the underlying cause of dementia.

Being studied: PiB and VAT

Conditions: Parkinsons

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • PD patients must exhibit three of the following cardinal signs: rest tremor, rigidity, bradykinesia, or postural instability; or two of these features with one of the first three displaying asymmetry.

Exclusion Criteria

  • history of head trauma, major neurological or psychiatric diseases other than Parkinson disease and dementia, e.g. stroke, multiple sclerosis, depression or schizophrenia.
  • severe systemic diseases.
  • inability to lie still for 90 minutes.
  • metallic implants, pacemakers, or any other contraindication to MRI.
  • refusal to consent to brain donation.

Recruiting US locations

  • Washington University in St. Louis

    St Louis, MO 63110

    Site contact: Susan Donovan, BSN · 314-362-6026 · donovan@wustl.edu

Study contacts (from the official record)

  • Andrea Slavik, RN, BSN · 314 273 8313 · andreaslavik@wustl.edu
  • Hailee Domash · 314 362 6026 · domash@wustl.edu
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Investigations of Dementia in Parkinson Disease (NCT02763683) | Bored Studies