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Ischemic Conditioning During Air tRansport Save penUmbral Tissue

Enrique Leira · NCT03481205

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 18–80 · All sexes
Healthy volunteers
Accepted
Study type
Interventional · Not applicable
Target enrollment
10
US sites recruiting
1
Study start
June 1, 2020
Record last updated
November 10, 2025

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

The purpose of this study is to demonstrate the feasibility of performing remote limb ischemic conditioning (RLIC) using the Doctormate device, a special blood pressure device used to perform RLIC, on patients with acute ischemic stroke due to large vessel occlusion being transported to a thrombectomy capable center by the helicopter.

Being studied: Ischemic conditioning device

Conditions: Acute Stroke

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • Age ≥18 and ≤ 80 years
  • Suspected acute ischemic stroke with symptoms suggestive of large vessel occlusion (aphasia, agnosia, neglect, visual field cut, and gaze preference).
  • Patient screened for rtPA, and rtPA administered if eligible
  • Subject or legally authorized representative able to provide consent at the time of the assessment
  • NIHSS 6-20

Exclusion Criteria

  • Any intracranial hemorrhage (parenchymal, subarachnoid, subdural, epidural) on CT scan at the community hospital
  • History of upper or lower extremity ischemia, known subclavian, brachial artery, iliac or femoral artery stenosis, subclavian steal syndrome, any upper or lower extremity soft tissue, orthopedic or vascular injury, or mastectomy or other procedure that may contraindicate taking blood pressure or having a cuff on the arm or leg for the conditioning treatment
  • History of diabetes mellitus
  • Enrollment in another clinical trial
  • Patient incarcerated
  • Pregnancy. Patients ages 18-55 will need to have a negative urine or blood based pregnancy test.
  • Agitation deemed unsafe for ischemic preconditioning testing.
  • Arteriovenous fistula in upper limb

Recruiting US locations

  • University of Iowa

    Iowa City, IA 52242

    Site contact: Enrique Leira, MD

Study contacts (from the official record)

  • Amir Shaban, MD · 3193568755 · amir-shaban@uiowa.edu
All neurology studies in Iowa →
Ischemic Conditioning During Air tRansport Save penUmbral Tissue (NCT03481205) | Bored Studies