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RecruitingAccepts healthy volunteersPhase 2

Kick-Nic! Youth Quit Vaping App

Yale University · with National Cancer Institute (NCI) · NCT06662305

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 12–19 · All sexes
Healthy volunteers
Accepted
Study type
Interventional · Phase 2
Target enrollment
306
US sites recruiting
1
Study start
January 7, 2025
Record last updated
July 31, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

High school and middle school students who want to quit vaping will be randomized to receive the Kick-Nic! app or a control NCI website to determine the efficacy of the app for vaping cessation. Participants will be screened for eligibility, then go through an 8 week treatment period where they will be given access to use the Kick-Nic! app or referred to the NCI Quit Vaping website. This will be followed by 1.5, 3, 4.5 and then 6 month follow up visits. Qualitative interviews with participants and school staff will also be conducted to obtain feedback on the app and best ways to implement/disseminate the app.

Abstinence rates will be assessed biweekly during treatment including at end of treatment (EOT), and then at 1.5, 3, 4.5 and then 6 months follow ups (FU). Biochemical verification (salivary cotinine \< 30 ng.ml) of self-reports of abstinence will be conducted at EOT and 6-month FU.

Being studied: Kick-Nic! mobile phone application; NCI Quit Vaping website

Conditions: Nicotine Vaping

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • high school or middle school aged youth (12-19 years old),
  • regular current (past month) e-cig users using nicotine-containing e-cigs at least 1 day/week.
  • want to quit using e-cigarettes.
  • have a smartphone with data/WIFI plan in order to access and utilize the KickNic! app

Exclusion Criteria

  • Those who have non-stable (\<2 months) use of anxiolytics, antidepressants, and other psychostimulants or have a history of psychosis or any significant current psychiatric/medical condition that would increase risk will be excluded.

Recruiting US locations

  • Yale University School of Medicine (Connecticut Mental Health Center)

    New Haven, CT 06519

    Site contact: Thomas Liss · 203-444-7545 · thomas.liss@yale.edu

Study contacts (from the official record)

  • Thomas Liss · 2034447545 · thomas.liss@yale.edu
All smoking & vaping studies in Connecticut →
Kick-Nic! Youth Quit Vaping App (NCT06662305) | Bored Studies