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Linking Somatic Mutation Rate With Baseline Exposure in East Palestine

Case Comprehensive Cancer Center · with National Institutes of Health (NIH), National Institute of Environmental Health Sciences (NIEHS) · NCT06357845

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 18+ · All sexes
Healthy volunteers
Accepted
Study type
Interventional · Not applicable
Target enrollment
500
US sites recruiting
1
Study start
August 16, 2024
Record last updated
March 16, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

The goal of this study is to This research team is conducting this study to develop methods to measure the biological impact of exposure to the chemicals released following the February 3, 2023 train derailment on residents of East Palestine, Ohio, and surrounding communities. The main question it aims to answer is:

  • What biological impact will be measured based on DNA damage?
  • In participants who provide a biospecimen, how are biomarker changes related to proximity to the derailment and variations in residents' health histories and behaviors?

Participants will

  • Complete a brief survey asking about experiences related to the February 3, 2023 train derailment, health experiences, and concerns following the derailment, and background information regarding health history.
  • Possibly contribute biospecimens such as blood, spit, hair, and/or toenail clippings.
  • Receive communication about study updates and future research opportunities.
  • A total of 40 study participants will be recruited to participate in a 90-minute interview. The interviews will be video and audio recorded.

Being studied: Survey; Biological specimen collection; Communications about study updates and future research opportunities; Qualitative interview

Conditions: Somatic Mutation

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • Residence on February 3rd, 2023 in Columbiana County, Ohio, Mahoning County, Ohio, Beaver County, PA, or Lawrence County, PA.
  • Current residence in the United States.

Exclusion Criteria

  • Address provided for February 3rd, 2023 not in Columbiana County, Ohio, Mahoning County, Ohio, Beaver County, PA, or Lawrence County, PA
  • Invalid address provided for February 3rd, 2023 residence.

Recruiting US locations

  • Case Western Reserve University, Case Comprehensive Cancer Center

    Cleveland, OH 44195

    Site contact: Fredrick Schumacher, PhD

Study contacts (from the official record)

  • Fredrick R Schumacher, PhD · 216-368-0351 · healthyfutures@case.edu
All healthy volunteers studies in Ohio →
Linking Somatic Mutation Rate With Baseline Exposure in East Palestine (NCT06357845) | Bored Studies