Liposomal Bupivacaine Vs Bupivacaine with Dexmedetomidine in Erector Spinae Plane Blocks for Mastectomies

Inclusion Criteria

• Patients requiring any variation of mastectomy with or without axillary lymph node dissection.
• Patient agrees to a peripheral nerve block.
• Patient agrees to be a study participant.
• APS team believes a peripheral nerve block would be appropriate for the patient after reviewing medical/surgical history.
• Surgeon agrees with the block plan by APS.

Exclusion Criteria

• Patient declines a peripheral nerve block.
• Patient declines to be a study participant.
• APS team believes a peripheral nerve block is not clinically indicated.
• Surgeon does not want a peripheral nerve block.
• Patient has allergy to local anesthestic.
• Patient has an active infection at the site of the peripheral nerve block.
• Patient with pre-existing neural deficits along the distribution of the block.
• Patient with coagulopathy.
• Patient taking antithrombotic drugs outside the ASRA guidelines.
• Patients weight is less that 50 kg due to concerns for local anesthetic toxicity syndrome.