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Long-term COVID and Rehabilitation

VA Office of Research and Development · NCT05373043

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 18+ · All sexes
Healthy volunteers
Accepted
Study type
Interventional · Not applicable
Target enrollment
300
US sites recruiting
1
Study start
November 1, 2022
Record last updated
July 30, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

The proposed focuses on improving both morbidity and mortality in older Veterans and those recovering from COVID-19 by developing rehabilitation therapies to augment vascular endothelial function by combating the oxidative stress and inflammation associated with aging and further induced by COVID-19. The investigators expected outcomes will have an important positive impact because they will provide scientifically sound recommendations for rehabilitation to improve vascular endothelial function and minimize the long-term consequences of COVID-19.

Being studied: Mitoquinone; Placebo

Conditions: Long-COVID

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • Long-COVID and COVID-recovered patients must have SARS-CoV-19 positive test near the time of COVID-19 diagnosis
  • Long-COVID and COVID-recovered patients must be 3-12 months post-initial COVID-19 diagnosis
  • Ability to sign informed consent

Exclusion Criteria

  • BMI >45 kg/m2
  • Unstable (\<6 months) or severe coronary artery disease (CAD-RADS score = 4A), peripheral artery disease (Ankle Brachial Index \<0.40), cerebrovascular disease (identified by previous stroke in last 12 months), severe COPD (=Stage III), uncontrolled hypertension (>160/100 mmHg), chronic kidney disease requiring dialysis, severe renal insufficiency (creatinine clearance \<30 by the Cockcroft-Gault formula), Alzheimer's disease, dementia
  • Orthopedic limitations that would prohibit exercise
  • Current smokers and individuals that stopped smoking in the last 10 years
  • Already taking Mito-Q or unwilling to cease dietary supplements for participation
  • Any other condition or event considered exclusionary by the PIs or a physician

Recruiting US locations

  • VA Salt Lake City Health Care System, Salt Lake City, UT

    Salt Lake City, UT 84148-0001

    Site contact: P Jon White, MD · (801) 582-1565 · Paul.White2@va.gov

Study contacts (from the official record)

  • Joel D Trinity, PhD · (801) 582-1565 · Joel.Trinity@va.gov
  • Russell S Richardson, PhD · (801) 582-1565 · r.richardson@hsc.utah.edu
All healthy volunteers studies in Utah →
Long-term COVID and Rehabilitation (NCT05373043) | Bored Studies