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Lower Body Negative Pressure to Validate Physiological Monitors

Mayo Clinic · NCT07840144

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 18–55 · All sexes
Healthy volunteers
Accepted
Study type
Interventional · Not applicable
Target enrollment
50
US sites recruiting
1
Study start
September 30, 2026
Record last updated
September 24, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

The purpose of this research is to test the accuracy of non-invasive physiological monitors while the body responds to different levels of lower body negative pressure (LBNP).

Being studied: Lower Body Negative Pressure with Noninvasive Physiological Monitoring

Conditions: Physiological Stress

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • Non-obese (BMI\<30)
  • Non-smokers
  • Free of any systemic diseases including hypertension, diabetes, coronary artery disease, neurologic disease, or any other major medical co-morbidity.
  • Women will be either surgically sterilized or non-pregnant as determined by a urine pregnancy test (within 48 hours of the study day)

Exclusion Criteria

  • Individuals taking GLP-1 medications or compounds known to affect responses of the autonomic nervous system to orthostatic stress (e.g., β-blockers)
  • Pregnant women

Recruiting US locations

  • Mayo Clinic

    Rochester, MN 55905

    Site contact: Pamela Engrav · 507-255-6938

Study contacts (from the official record)

  • Pamela Engrav · 507-255-6938 · engrav.pamela@mayo.edu
  • Ronee Harvey · 507-255-1466 · harvey.ronee@mayo.edu
All healthy volunteers studies in Minnesota →
Lower Body Negative Pressure to Validate Physiological Monitors (NCT07840144) | Bored Studies