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Magnetic Resonance Spectroscopy Studies of Cardiac Muscle Metabolism

Johns Hopkins University · with National Heart, Lung, and Blood Institute (NHLBI) · NCT00181259

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 18+ · All sexes
Healthy volunteers
Accepted
Study type
Observational
Target enrollment
500
US sites recruiting
1
Study start
January 1988
Record last updated
March 9, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

The metabolism of the heart provides the chemical energy needed to fuel ongoing normal heart contraction. Magnetic resonance spectroscopy is a technique used in a MRI scanner that can be used to measure and study heart metabolism directly but without blood sampling or obtaining tissue biopsies. One of the hypotheses this study aims to investigate is whether energy metabolism is reduced in heart failure and whether that contributes to the poor heart function.

Conditions: Heart Failure, Congestive

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • age > 18 years
  • Healthy subjects: no history of heart disease
  • Dilated cardiomyopathy: history of heart failure, ejection fraction (EF) \<40%
  • Left ventricular hypertrophy: wall thickness >1.2cm
  • Coronary artery disease: >50% coronary lesion or positive stress test

Exclusion Criteria

  • contraindication to MRI

Recruiting US locations

  • Johns Hopkins Medical Institutions

    Baltimore, MD 21205

    Site contact: Tricia Steinberg, RN, MSN · 443-287-3469 · asteinb3@jhmi.edu

Study contacts (from the official record)

  • Robert G. Weiss, MD · 410-955-1703 · rweiss@jhmi.edu
All heart & blood pressure studies in Maryland →
Magnetic Resonance Spectroscopy Studies of Cardiac Muscle Metabolism (NCT00181259) | Bored Studies