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RecruitingAccepts healthy volunteersEarly Phase 1

Measuring Acute Drug Demand in Humans

University of Maryland, Baltimore · with National Institute on Drug Abuse (NIDA) · NCT05829655

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 18–65 · All sexes
Healthy volunteers
Accepted
Study type
Interventional · Early Phase 1
Target enrollment
75
US sites recruiting
1
Study start
August 8, 2023
Record last updated
June 23, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

This research is being done to evaluate whether suvorexant may reduce the use of, subjective liking, and demand for various drugs.

Being studied: Drug A (Blinded Drug); Drug B (Blinded Drug); Drug C (Blinded Drug); Drug D (Blinded Drug); Suvorexant (20mg/day); Placebo

Conditions: Opioid Use Disorder; Opioid Dependence

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • Age between 18 and 65 years old
  • Meets Diagnostic and Statistical Manual-5 criteria for Opioid Use Disorder (OUD) (moderate or severe)
  • Lifetime substance use history criterion [blinded]
  • Medically cleared to take suvorexant and blinded study medications
  • Be in good general health based on a physical examination, medical history, vital signs, and screening urine and blood tests

Exclusion Criteria

  • Pregnant or breast feeding
  • Seeking opioid use treatment
  • Significant mental health or physical disorder that is expected to interfere with study participation as assessed by the study physicians or medical staff
  • Known contraindications or allergies to suvorexant and/or the blinded study medications

Recruiting US locations

  • General Clinical Research Center

    Baltimore, MD 21201

    Site contact: Justin Strickland, PhD · 667-354-3516 · jstrickland@som.umaryland.edu

Study contacts (from the official record)

  • Justin Strickland, PhD · 667-354-3516 · jstrickland@som.umaryland.edu
All healthy volunteers studies in Maryland →
Measuring Acute Drug Demand in Humans (NCT05829655) | Bored Studies