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Mechanisms of Improving Fecal Continence Muscles Motor Function

Medical College of Wisconsin · NCT06532123

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 18+ · All sexes
Healthy volunteers
Accepted
Study type
Interventional · Not applicable
Target enrollment
340
US sites recruiting
1
Study start
July 15, 2025
Record last updated
October 23, 2025

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

The investigators hypothesize that different continence muscles have different fatigue characteristics and fatigue induced by resisted contractions will result in significant increase in contractility of the continence muscles and improvement of fecal incontinence severity.

Being studied: continence muscles resistance device

Conditions: Fecal Incontinence

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • Healthy volunteers without past or present history of fecal incontinence
  • Patients age 18 years and older with reduced anal resting and or squeeze pressure, reflecting weakness of the anal sphincters who can perform the study

Exclusion Criteria

  • Any one less than 18 years old
  • Neurological disorders like dementia, cerebrovascular diseases
  • Muscle diseases like muscular dystrophy, myopathies
  • Inflammatory bowel disease or celiac disease
  • Neuro-muscular junction disorders/myasthenia gravis, Eaton-Lambert syndrome
  • Organ prolapse, large rectocele(>2cm), rectal intussusception
  • Hip dysplasia or recent hip surgery and immobile patients.
  • Patients with complete normal anal resting and squeeze pressure
  • Impaired rectal evacuation (dyssynergy defecation)
  • Fecal incontinence completely due to loss of rectal sensation
  • Subjects unable to contract their external anal sphincter at all

Recruiting US locations

  • Medical College of Wisconsin

    Milwaukee, WI 53086

    Site contact: Ling Mei, MD · 4148059694 · lmei@mcw.edu

Mechanisms of Improving Fecal Continence Muscles Motor Function (NCT06532123) | Bored Studies