Mechanisms of Improving Fecal Continence Muscles Motor Function
Medical College of Wisconsin · NCT06532123
Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.
Key facts
- Compensation
- Not posted. Ask the study team before screening.
- Who can join
- Ages 18+ · All sexes
- Healthy volunteers
- Accepted
- Study type
- Interventional · Not applicable
- Target enrollment
- 340
- US sites recruiting
- 1
- Study start
- July 15, 2025
- Record last updated
- October 23, 2025
Status re-checked against ClinicalTrials.gov within the last 12 hours.
What the study is about
The investigators hypothesize that different continence muscles have different fatigue characteristics and fatigue induced by resisted contractions will result in significant increase in contractility of the continence muscles and improvement of fecal incontinence severity.
Being studied: continence muscles resistance device
Conditions: Fecal Incontinence
Eligibility criteria
Copied from the official record. The study team makes the final decision at screening.
Show full criteria
Inclusion Criteria
- Healthy volunteers without past or present history of fecal incontinence
- Patients age 18 years and older with reduced anal resting and or squeeze pressure, reflecting weakness of the anal sphincters who can perform the study
Exclusion Criteria
- Any one less than 18 years old
- Neurological disorders like dementia, cerebrovascular diseases
- Muscle diseases like muscular dystrophy, myopathies
- Inflammatory bowel disease or celiac disease
- Neuro-muscular junction disorders/myasthenia gravis, Eaton-Lambert syndrome
- Organ prolapse, large rectocele(>2cm), rectal intussusception
- Hip dysplasia or recent hip surgery and immobile patients.
- Patients with complete normal anal resting and squeeze pressure
- Impaired rectal evacuation (dyssynergy defecation)
- Fecal incontinence completely due to loss of rectal sensation
- Subjects unable to contract their external anal sphincter at all
Recruiting US locations
Medical College of Wisconsin
Milwaukee, WI 53086
Site contact: Ling Mei, MD · 4148059694 · lmei@mcw.edu
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