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Mechanisms of Pregnancy Vascular Adaptations

University of Wisconsin, Madison · with National Heart, Lung, and Blood Institute (NHLBI) · NCT03806283

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 18–40 · Women only
Healthy volunteers
Accepted
Study type
Observational
Target enrollment
166
US sites recruiting
1
Study start
November 20, 2018
Record last updated
January 20, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

The investigators will collect omental tissue (research surgical excision) and placental tissue (standard of care clinical delivery) from both preeclamptic and non-preeclamptic women during their c-section and use these samples to study the blood vessels, specifically the expression/activation of the AT2R.

Being studied: Omental Biopsy

Conditions: Pre-Eclampsia; Vascular Diseases

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • Female
  • Ages 18 to 40 years old
  • Singleton gestation between 28 weeks, 0 days and 41 weeks, 0 days gestational age at the time of consent
  • Undergoing caesarean section, either planned or otherwise with or without trial of labor

Exclusion Criteria

  • Treatment of severe hypertension by antihypertensive or use of magnesium sulfate after the patient is hospitalized for the diagnosis of preeclampsia.
  • Any major fetal structural anomalies or aneuploidies
  • Undergoing cesarean section for placental abruption or bleeding complications.
  • Singleton gestation not within 36 weeks, 0 days and 41 weeks, 0 days gestational age at the time of enrollment (delivery)

Recruiting US locations

  • UnityPoint Health-Meriter Hospital

    Madison, WI 53715

    Site contact: Sathish Kumar, PhD

Study contacts (from the official record)

  • UW Ob/Gyn Human Subjects Core · 608-890-3345 · research.crc_obgyn@wisc.edu
All heart & blood pressure studies in Wisconsin →
Mechanisms of Pregnancy Vascular Adaptations (NCT03806283) | Bored Studies