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Menthol, Inflammation, and Nicotine Transition Study

Rosalind Franklin University of Medicine and Science · with National Heart, Lung, and Blood Institute (NHLBI) · NCT06232447

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 21–85 · All sexes
Healthy volunteers
Accepted
Study type
Interventional · Not applicable
Target enrollment
68
US sites recruiting
1
Study start
March 26, 2024
Record last updated
April 16, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

This study will focus on examining the potential impact of menthol flavoring in cigarettes on biomarkers of systemic inflammation as a subclinical indicator of cardiovascular disease risk.

Being studied: Cigarette Type Switching

Conditions: Cigarette Smoking; Inflammatory Response

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion criteria

  • Men and women between 21-85 years old
  • Currently uses menthol cigarettes
  • Daily smoking rate of ≥5 cigarettes/day for ≥1 year
  • Currently own and regularly use an iOS/Android smartphone device able to download the LifeData application
  • Able to read and communicate fluently in English

Exclusion criteria

  • Currently pregnant or breastfeeding
  • Actively trying to quit smoking
  • Current heavy alcohol use
  • Frequent use of non-menthol cigarettes, other smoking products, or illicit substances
  • History of severe medical/psychiatric condition or treatment

Recruiting US locations

  • Rosalind Franklin University of Medicine and Science

    North Chicago, IL 60064

    Site contact: Nancy C Jao, PhD · 847-578-8747 · nancy.jao@rosalindfranklin.edu

Study contacts (from the official record)

  • Nancy C Jao, PhD · 847-578-8747 · nancy.jao@rosalindfranklin.edu
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Menthol, Inflammation, and Nicotine Transition Study (NCT06232447) | Bored Studies