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Motivational Refinements for Facilitating Reinforcement Schedule Thinning

Rutgers, The State University of New Jersey · NCT05790668

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 3–17 · All sexes
Healthy volunteers
Accepted
Study type
Interventional · Not applicable
Target enrollment
30
US sites recruiting
2
Study start
October 24, 2023
Record last updated
August 12, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

Destructive behavior represents a comorbid condition of developmental disability for which risk increases with intellectual disability severity, communication deficits, and co-occurring autism spectrum disorder. Destructive behavior, such as self-injurious behavior and aggression, causes harm to the child and others and increases the risk for institutionalization, social isolation, physical restraint, medication overuse, and abuse. Clinicians have used functional analyses to identify the variables that reinforce destructive behavior and to develop effective, function-based treatments. Functional communication training (FCT) is an empirically supported, function-based treatment that decreases destructive behavior. Using FCT, the clinician teaches the child to use a functional communication response (FCR) to request the reinforcer maintaining destructive behavior, while placing destructive behavior on extinction. For example, if functional analysis results showed that attention reinforced destructive behavior, the clinician would provide attention when the child used the FCR ("Play with me, please") and would not provide attention for destructive behavior. Two limitations of FCT are that (a) schedules of reinforcement maintaining the FCR must often be thinned gradually to levels that are practical for caregivers to implement consistently in the home and in the community, and (b) this necessary process of reinforcement schedule thinning regularly causes destructive behavior to increase following initially effective treatment, a form of treatment relapse called resurgence. The current project aims to improve these limitations of FCT by (a) hastening the process of reinforcement schedule thinning by removing unnecessary schedule-thinning steps using the results of a progressive interval assessment and (b) mitigating the resurgence of destructive behavior by providing stimuli that highly compete with the reinforcer maintaining destructive behavior. The investigators will conduct a randomized clinical trial to evaluate the extent to which these two promising refinements to FCT improve the process of reinforcement schedule thinning, and an exploratory experiment will examine the interactive effects of these two approaches. This novel project has the potential to substantially improve standards of care guiding the treatment of severe destructive behavior and to improve the long-term outcomes for children and families afflicted by these debilitating behavior disorders.

Being studied: Traditional Schedule Thinning; PIA-Informed Schedule Thinning; PIA-Informed Schedule Thinning with Competing Stimuli

Conditions: Decreasing Destructive Behavior; Increasing Functional Communicative Behavior

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • boys and girls from ages 3 to 17
  • destructive behavior that occurs at least 10 times a day, despite previous treatment
  • destructive behavior reinforced by social consequences
  • stable protective supports for self-injurious behavior (e.g., helmet) with no anticipated changes during enrollment
  • on a stable psychoactive drug regimen for at least 10 half-lives per drug or drug free
  • stable educational plan and placement with no anticipated changes during the child's treatment

Exclusion Criteria

  • patients who do not meet the inclusion criteria
  • patients currently receiving 15 or more hours per week of treatment for their destructive behavior
  • Diagnostic and Statistical Manual-5 diagnosis of Rett syndrome or other degenerative conditions (e.g., inborn error of metabolism)
  • a comorbid health condition or major mental disorder that would interfere with study participation
  • occurrence of self-injury during study assessments that presents a risk of serious or permanent harm (e.g., detached retinas) based on routine clinical-risk assessment
  • patients requiring changes to protective supports for self-injury or drug treatment, but investigators will invite these patients to participate when protective supports and drug regimen are stable

Recruiting US locations

  • Douglass Developmental Disabilities Center

    New Brunswick, NJ 08901

    Site contact: Robert LaRue, Ph.D. · 8489324500 · larue@rutgers.edu

  • Rutgers University Center for Autism Research, Education, and Services

    Somerset, NJ 08873

    Site contact: Brian D Greer, Ph.D. · 8488008505 · brian.greer@rutgers.edu

Study contacts (from the official record)

  • Brian D Greer, Ph.D. · 8488008505 · brian.greer@rutgers.edu
  • Daniel R Mitteer, Ph.D. · 8488008506 · daniel.mitteer@rutgers.edu
Motivational Refinements for Facilitating Reinforcement Schedule… (NCT05790668) | Bored Studies