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Multifocal HD-tDCS and Motor Function

University of Michigan · with Medical University of South Carolina, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) · NCT06561165

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 65–85 · All sexes
Healthy volunteers
Accepted
Study type
Interventional · Not applicable
Target enrollment
40
US sites recruiting
1
Study start
February 25, 2025
Record last updated
October 20, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

The purpose of this study is to understand how the brain controls movement and how Non-invasive Brain Stimulation (NIBS) with a technique called High-density transcranial direct current stimulation (HD-tDCS) can alter brain processes to improve behavior. Participants in this study will be randomized to either HD-tDCS with standard intervention or personalized dose-controlled multifocal network-targeted HD-tDCS.

The hypothesis is that dexterous hand function will improve after a standard HD-tDCS dose and increase even more after personalized dose-controlled multifocal network-targeted HD-tDCS.

Being studied: Standard HD-tDCS intervention; Multifocal network targeted HD-tDCS intervention; Functional Magnetic Resonance Imaging (fMRI)

Conditions: Healthy

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • Participants should be in good health with normal or corrected-to-normal visual acuity
  • Right handed
  • No history of neurological disorder
  • English speaker
  • Able to provide written consent prior to admission

Exclusion Criteria

  • Left-handed
  • Participants are pregnant, suspect pregnancy or are attempting to become pregnant
  • Have a pacemaker, intracardiac lines or any other medically implanted device or medicine pump
  • Have cochlear hearing implants
  • Taking drugs known to influence neural receptors that facilitate neuroplasticity (see protocol)
  • Have non removable body piercings or have foreign objects in body
  • Have metal anywhere in the head that could increase risk of serious injury (not including braces, dental fillings, etc.) (see protocol)
  • Have a personal or family history of seizure/epilepsy
  • Taking prescription drugs that lower the threshold for seizures
  • Recent history of excessive alcohol consumption
  • History of alcohol addiction/dependence
  • Recent history of recreational drug use
  • History of drug addiction/dependence
  • Recent history of recreational drug use
  • History of drug addiction/dependence
  • Diagnosed with a stroke, brain hemorrhage, brain tumor, encephalitis.
  • Diagnosed with multiple sclerosis
  • Diagnosed with Parkinson's disease or Alzheimer's disease
  • Diagnosed with depression in the past 6 months
  • Diagnosed with attention deficit disorder, schizophrenia, manic depressive (bipolar) disorder
  • Diagnosed with normal pressure hydrocephalus or increased intra-cranial pressure
  • Diabetes requiring insulin treatment
  • Any serious heart disorder or liver disease

Recruiting US locations

  • University of Michigan

    Ann Arbor, MI 48109

    Site contact: Michael Vesia, PhD · 734-764-5237 · mvesia@umich.edu

Study contacts (from the official record)

  • Michael Vesia, PhD · 734-764-5237 · mvesia@umich.edu
All healthy volunteers studies in Michigan →
Multifocal HD-tDCS and Motor Function (NCT06561165) | Bored Studies