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Neural Mechanisms of Real-world Emotions and Internalizing

University of Miami · with National Institute of Mental Health (NIMH) · NCT07891624

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 18–35 · All sexes
Healthy volunteers
Accepted
Study type
Interventional · Not applicable
Target enrollment
144
US sites recruiting
1
Study start
August 24, 2026
Record last updated
October 23, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

This study utilizes mobile health methods, including smartphone technology, subjective self-reports measures of emotion, behavioral tasks, functional Magnetic Resonance Imaging (fMRI), physiological measures of attention and arousal, and measures of health and social support to identify neural mechanisms associated with individual differences in the temporal course of emotional responses. The aim of this project is to utilize real-world and personally relevant events as stimuli to better understand how the temporal course of emotional responses relate to risk for developing mental disorders.

Being studied: Academic Performance Feedback

Conditions: Major Depression; Generalized Anxiety; Emotions

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • Individuals who are between 18 - 35 years old. [Reason: to be able to provide informed consent, and to minimize variation in functional and structural differences in brain]
  • Individuals who are fluent English speakers. [Reason: to understand study instructions \& questionnaires]
  • Smart phone access. [Reason: to answer the questionnaires that are administered throughout the study.

Exclusion Criteria

  • Women who are pregnant or breast feeding and are no more than six months post-partum. [Reason: may be unsafe for fetus, may affect outcome measure(s)]
  • Individuals who are excluded based on attached metal resonance Screening Form (Note: this form has already been approved by the Institutional Review Board (IRB for other protocols). [Reason: necessary to participate in MRI research protocol]
  • Individuals whose BMI is above 35. [Reason: must fit into fMRI scanner]
  • Individuals who have claustrophobia. [Reason: to be able to stay in MRI scanner]
  • Individuals who are unable, in the judgment of the investigator, to comply with directions and/or tolerate the procedures required for participation in this trial. [Reason: to be able to understand instructions and ensure safety]
  • Individuals who are unable to safely undergo MRI scanning. [Reason: to be able to undergo MRI scanning]

Recruiting US locations

  • University of Miami

    Coral Gables, FL 33146

    Site contact: Aaron S Heller, PhD · 305-284-9498 · axh825@miami.edu

Study contacts (from the official record)

  • Aaron S Heller, PhD · 305-284-9498 · axh825@miami.edu
Neural Mechanisms of Real-world Emotions and Internalizing (NCT07891624) | Bored Studies