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Neurofeedback to Reduce Spontaneous Recovery of Threat Expectancy

Trustees of Princeton University · with National Institute of Mental Health (NIMH) · NCT07122739

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 18–50 · All sexes
Healthy volunteers
Accepted
Study type
Interventional · Not applicable
Target enrollment
40
US sites recruiting
1
Study start
July 17, 2025
Record last updated
February 23, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

This study tests the efficacy of a new behavioral intervention with the goal of reducing spontaneous recovery of threat expectancy in healthy adults. This real-time functional magnetic resonance imaging (fMRI) neurofeedback intervention delivers feedback based on a functional connection between the prefrontal cortex and the hippocampus.

Being studied: Active Real-time fMRI Neurofeedback; Sham Real-time fMRI neurofeedback

Conditions: Healthy

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • Adults aged 18-50
  • No history of psychiatric disorders or neurological disorders affecting the central nervous system.
  • Are not currently taking psychoactive medication or drugs of abuse.
  • Must be eligible to enter an MRI (i.e., no permanent metal or medical implants)
  • Normal color vision
  • Right-handed
  • Full reading and writing English comprehension
  • Must exhibit spontaneous recovery behavior as determined by an experimenter in a prescreening experimental session
  • Must be able to provide informed consent

Exclusion Criteria

  • Pregnancy (female participants)
  • Outside of age range
  • History of psychiatric or neurological disease
  • Currently taking psychoactive medication or drugs of abuse
  • Color blindness
  • Primary left-handedness
  • Less than full reading and writing English comprehension
  • Do not exhibit spontaneous recovery behavior as determined by an experimenter in a prescreening experimental session
  • Refusing to provide informed consent

Recruiting US locations

  • Princeton Neuroscience Institute

    Princeton, NJ 08540

    Site contact: Augustin C. Hennings, Ph.D. · gus.hennings@princeton.edu

Study contacts (from the official record)

  • Augustin C. Hennings, Ph.D. · 609-258-5032 · gus.hennings@princeton.edu
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Neurofeedback to Reduce Spontaneous Recovery of Threat Expectancy (NCT07122739) | Bored Studies