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Neuroimaging Reveals Treatment-related Changes in DLD

University of Cincinnati · with Children's Hospital Medical Center, Cincinnati, University of Toronto · NCT05268341

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 4–5 · All sexes
Healthy volunteers
Accepted
Study type
Interventional · Not applicable
Target enrollment
100
US sites recruiting
4
Study start
May 24, 2022
Record last updated
May 26, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

Children with developmental language disorders (DLD, aka specific language impairment), a prevalent pediatric disorder, experience hallmark grammar deficits with life-long impacts on educational and occupational outcomes. While effective and early interventions can mitigate the impact of DLD, not enough is known about the neural basis of DLD in young children, yet is needed to inform the design of more individualized interventions. This project uses neuroimaging, along with behavioral methods, with the goal of better understanding the memory-language mechanisms that underlie grammar learning and impairment, while also considering their association to treatment-related changes in preschoolers with DLD.

Being studied: My Sentence Builder

Conditions: Developmental Language Disorder

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • ages 48-71 months
  • average nonverbal intelligence quotient (IQ)
  • enrolled in participating center
  • typically developing (receptive and expressive language, social, articulation, other)
  • DLD for expressive grammar
  • typical oral motor function
  • typical social/pragmatics skills
  • average hearing thresholds
  • monolingual and native Standard English speakers
  • does not have any uncorrected vision challenges

Exclusion Criteria

  • receiving co-occurring speech-language or other intervention for communication
  • not MRI safe
  • special education placement of child based on ability or behavior

Recruiting US locations

  • Empower Learn Create INC

    Cincinnati, OH 45220

    Site contact: Sandy Paul · 513-961-2825 · spaul@empowerlearncreate.org

  • CWFF CHild Development Center

    Cincinnati, OH 45229

    Site contact: Robin Brandy · 513-569-5662 · cwffchilddevelopment@gmail.com

  • Wesley Education Center for Children and Families

    Cincinnati, OH 45229

    Site contact: Carla Butler · 513-845-7990 · crbutler0915@yahoo.com

  • University of Cincinnati

    Cincinnati, OH 45267

    Site contact: Amber Yusko, MA · 513-558-1416 · meadowae@ucmail.uc.edu

Study contacts (from the official record)

  • Karla N Washington, PhD · 513-558-8533 · washink2@ucmail.uc.edu
  • Jennifer J Vannest, PhD · 513-558-8518 · vannesjr@ucmail.uc.edu
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Neuroimaging Reveals Treatment-related Changes in DLD (NCT05268341) | Bored Studies