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Novel Couple-Based Mindfulness Intervention for Metastatic Colorectal Cancer

University of Colorado, Denver · with National Cancer Institute (NCI) · NCT07759921

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 18–85 · All sexes
Healthy volunteers
Accepted
Study type
Interventional · Not applicable
Target enrollment
90
US sites recruiting
1
Study start
December 2026
Record last updated
August 14, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

The overall objective of this study is to learn whether a newly developed couple-based mindfulness program (Mindful PaCT) is practical to complete (feasible), helpful and well-received (acceptable), and relevant for patients with metastatic colorectal cancer (mCRC) and their partners.

Being studied: Couple-based Mindfulness Intervention; Health and Wellness Education Control Condition

Conditions: Colorectal Cancer; Metastatic Colorectal Cancer (CRC)

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • Provision to sign and date the consent form.
  • Stated willingness to comply with all study procedures and be available for the duration of the study.
  • Be aged > 18 years to 85.
  • Fluent in English language. All study materials, including the informed consent form, participant workbooks, and questionnaires, are currently available only in English. Participation requires the ability to independently read and engage with written study materials (including the participant workbook), which are integral to the intervention session content and home practices. Therefore, individuals who are unable to read study materials in English are not eligible to participate. At this time, the intervention has not been translated or validated in other languages, therefore participation is limited to individuals who can read, speak, and understand English to ensure that participants are able to fully engage with study activities.
  • Be a person (i.e., patient) diagnosed with metastatic colorectal cancer (mCRC) or a partner (e.g., spouse) of someone diagnosed with mCRC.
  • Indicates a score >0 on the Distress Thermometer
  • Has access to computer/internet through with video-conferencing (phone, laptop, tablet, desktop computer)

Additional eligibility criteria include

Additional patient participant inclusion criteria:

  • Has a current diagnosis of metastatic (Stage IV, recurrent) colorectal cancer
  • Has an ECOG status \<2 or otherwise deemed appropriate for study participation by a clinician
  • Is in a committed relationship with a romantic partner for >6 months. Monogamy is not required for eligibility; however, in cases of polyamorous relationships, the patient will designate a primary partner for participation in the study.

Additional partner participant inclusion criteria:

  • Has been in a committed relationship >6 months with a patient who meets the above eligibility criteria

Eligibility for relationship status will be self-reported by participants during recruitment.

Exclusion Criteria

  • One or both members of the couple has an active or poorly controlled serious mental illness (e.g., psychotic disorder), cognitive impairment (e.g., dementia), or medical condition (e.g., significant impaired sight/hearing) that would compromise participation.
  • The couple is currently in active couples (e.g., marital) therapy together.

Participants who are physically or mentally too ill to participate or those with major cognitive impairments are excluded because they may not be able to engage with intervention sessions, surveys. No exclusions will be made based on sexual orientation, race, gender, or other sociodemographic features. Because patients with mCRC are living longer, and patients and partners can experience distress at various times since their diagnosis, we do not limit participation by time since diagnosis.

Recruiting US locations

  • University of Colorado Hospital

    Aurora, CO 80045

    Site contact: Kaylee Ortega · 303-724-8895 · kaylee.ortega@cuanschutz.edu

Study contacts (from the official record)

  • Kaylee Ortega · 3037248895 · kaylee.ortega@cuanschutz.edu
Novel Couple-Based Mindfulness Intervention for Metastatic… (NCT07759921) | Bored Studies