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RecruitingAccepts healthy volunteersPhase 1

OMAR Opioid Use Disorder

Yale University · with National Institute on Drug Abuse (NIDA) · NCT05683184

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 18+ · All sexes
Healthy volunteers
Accepted
Study type
Interventional · Phase 1
Target enrollment
30
US sites recruiting
1
Study start
March 10, 2023
Record last updated
September 10, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

The goal of this research study is to examine the endocannabinoid (eCB) function in vivo in individuals with opioid use disorder (OUD) by measuring cannabinoid receptor 1 (CB1R) availability.

Being studied: [11C]OMAR

Conditions: Healthy Control; Opioid Use Disorder

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • Able to provide informed consent
  • Male and female 18 years and older
  • DSM-5 diagnosis of opioid use disorder (for OUD group)
  • Physically healthy i.e., no clinically unstable medical conditions
  • Written informed consent and have capacity to consent and comply with study procedures

Exclusion Criteria

  • Current neuro-psychiatric illness or severe systemic disease (opioid use disorder is permitted in the OUD group).
  • Presence of ferromagnetic metal in the body or heart pacemaker
  • Have had exposure to ionizing radiation that in combination with the study tracer would result in a cumulative exposure that exceeds recommended exposure limits
  • Are claustrophobic
  • Hematocrit values lower than 30

Recruiting US locations

  • Connecticut Mental Health Center, Clinical Neuroscience Research Unit

    New Haven, CT 06519

    Site contact: Abby Dewey · 475-441-4190 · abigail.dewey@yale.edu

Study contacts (from the official record)

  • Anahita Bassir Nia, MD · 203-974-7540 · anahita.bassirnia@yale.edu
  • Abby Dewey · 475-441-4190 · abigail.dewey@yale.edu
All healthy volunteers studies in Connecticut →
OMAR Opioid Use Disorder (NCT05683184) | Bored Studies