Omega-3 Fatty Acids and Subconcussive Head Impacts
Indiana University · with National Institute of Neurological Disorders and Stroke (NINDS) · NCT06736925
Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.
Key facts
- Compensation
- Not posted. Ask the study team before screening.
- Who can join
- Ages 18–30 · All sexes
- Healthy volunteers
- Accepted
- Study type
- Interventional · Not applicable
- Target enrollment
- 208
- US sites recruiting
- 1
- Study start
- February 28, 2025
- Record last updated
- April 29, 2026
Status re-checked against ClinicalTrials.gov within the last 12 hours.
What the study is about
The purpose of the proposed double-blind, randomized placebo-controlled trial is to understand how supplementation with fish oil [docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA)] promote brain health against soccer heading. The study involves taking DHA+EPA or placebo, questionnaires, blood draws, brain imaging, tests to evaluate heart function, and soccer headings.
Being studied: Omega-3 Fatty Acids (EPA plus DHA); Organic soybean oil; Soccer Heading Model
Conditions: Subconcussive Head Impact; Omega-3 Fatty Acids
Eligibility criteria
Copied from the official record. The study team makes the final decision at screening.
Show full criteria
Inclusion Criteria
- Between age 18-30
- Current or former soccer player
- At least 5 years of soccer heading experience
- Have internet access
- Willing to commit to avoid any sport activity that purposefully uses one's head to maneuver during the study period (American football, ice-hockey, rugby, wrestling, and soccer heading).
Exclusion Criteria
- Any head or neck injury within 6 months before the study
- Implanted metal/magnetic devices (e.g., orthodontic braces
- Diagnosed autonomic or cardiovascular diseases (e.g., hypertension)
- Consuming oily fish (2 servings or more/month: salmon, bluefin, swordfish, anchovies)
- Allergy to fish or shellfish
- Consuming omega-3 FA supplements including plant-based (e.g., flaxseed) in the past 3 months.
- Pregnancy
Recruiting US locations
Indiana University School of Public Health
Bloomington, IN 47405
Site contact: Kei Kawata · 812-855-5244 · kkawata@indiana.edu
Study contacts (from the official record)
- Kei Kawata · 812-855-5244 · kkawata@indiana.edu
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