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Omega-3 Fatty Acids and Subconcussive Head Impacts

Indiana University · with National Institute of Neurological Disorders and Stroke (NINDS) · NCT06736925

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 18–30 · All sexes
Healthy volunteers
Accepted
Study type
Interventional · Not applicable
Target enrollment
208
US sites recruiting
1
Study start
February 28, 2025
Record last updated
April 29, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

The purpose of the proposed double-blind, randomized placebo-controlled trial is to understand how supplementation with fish oil [docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA)] promote brain health against soccer heading. The study involves taking DHA+EPA or placebo, questionnaires, blood draws, brain imaging, tests to evaluate heart function, and soccer headings.

Being studied: Omega-3 Fatty Acids (EPA plus DHA); Organic soybean oil; Soccer Heading Model

Conditions: Subconcussive Head Impact; Omega-3 Fatty Acids

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • Between age 18-30
  • Current or former soccer player
  • At least 5 years of soccer heading experience
  • Have internet access
  • Willing to commit to avoid any sport activity that purposefully uses one's head to maneuver during the study period (American football, ice-hockey, rugby, wrestling, and soccer heading).

Exclusion Criteria

  • Any head or neck injury within 6 months before the study
  • Implanted metal/magnetic devices (e.g., orthodontic braces
  • Diagnosed autonomic or cardiovascular diseases (e.g., hypertension)
  • Consuming oily fish (2 servings or more/month: salmon, bluefin, swordfish, anchovies)
  • Allergy to fish or shellfish
  • Consuming omega-3 FA supplements including plant-based (e.g., flaxseed) in the past 3 months.
  • Pregnancy

Recruiting US locations

  • Indiana University School of Public Health

    Bloomington, IN 47405

    Site contact: Kei Kawata · 812-855-5244 · kkawata@indiana.edu

Study contacts (from the official record)

  • Kei Kawata · 812-855-5244 · kkawata@indiana.edu
Omega-3 Fatty Acids and Subconcussive Head Impacts (NCT06736925) | Bored Studies