Omega-3 Fatty Acids as Regulators of Brown Adipose Tissue During Cold Exposure
Indiana University · NCT05822141
Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.
Key facts
- Compensation
- Not posted. Ask the study team before screening.
- Who can join
- Ages 18–40 · All sexes
- Healthy volunteers
- Accepted
- Study type
- Interventional · Not applicable
- Target enrollment
- 30
- US sites recruiting
- 1
- Study start
- June 12, 2023
- Record last updated
- May 26, 2026
Status re-checked against ClinicalTrials.gov within the last 12 hours.
What the study is about
This clinical trial will assess the whether fish oil supplementation can modulate brown fat activation, shivering, thermal comfort and skin blood flow during cold exposure.
Being studied: Fish Oil; Placebo
Conditions: Cold Exposure
Eligibility criteria
Copied from the official record. The study team makes the final decision at screening.
Show full criteria
Inclusion Criteria
- Male and female, between the ages of 18 to 40 years.
- Body Mass Index (BMI) of 18.5 to 24.9 kg/m2
- Considered "moderately to highly active" by the International Physical Activity Questionnaire (IPAQ) and the Physical Activity Readiness Questionnaire (PAR-Q+)
Exclusion Criteria
- History of smoking or recreational smoking, hyperlipidemia, hypertension/cardiovascular disease, diabetes, renal disease, neurological disease, metabolic disease, and bleeding disorders or delayed clotting time.
- Taking SSRI's (antidepressants and anxiety medication), ADD/ADHD medication, and chronically consume pain medication (Aleve, Tylenol, CBD, etc).
- Have or have had chronic disorders of the rectum (e.g., cancer, surgery, active hemorrhoids, etc.) or who currently have related acute conditions (diarrhea, constipation, etc.).
- Have or have had a diagnosis of disorders related to immune suppression and/or autoimmune disease.
- Are pregnant or planning on being pregnant.
- Resting blood pressure of > 130mmHg systolic or 90 mmHg diastolic.
- Resting Pulse rate of > 100 bpm.
- History of regularly consuming fish oil supplements and/or regularly eating more than one fish meal per week.
- Consuming more than one fish meal per week during the study.
Recruiting US locations
Human Perfromance Lab, Indiana University
Bloomington, IN 47405
Site contact: Timothy Mickleborough, PhD · tmickleb@inidana.edu
Study contacts (from the official record)
- Timothy D Mickleborough, PhD · 812-855-0753 · tmickleb@indiana.edu
- Abigail S Sogard, B.S. · asogard@iu.edu
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