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Optical Coherence Tomography Angiography in Subjects With Retinal Vascular Disease

Johns Hopkins University · with National Eye Institute (NEI) · NCT04505618

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 18–99 · All sexes
Healthy volunteers
Accepted
Study type
Interventional · Not applicable
Target enrollment
1050
US sites recruiting
1
Study start
October 1, 2019
Record last updated
June 17, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

This study will perform a prospective, longitudinal analysis of clinical and imaging findings from normal controls and subjects with retinal vascular disease to better define the diagnostic imaging criteria that signify change in disease stage. This includes disease progression in early stages of disease or disease regression with appropriate standard-of-care treatment.

Being studied: Swept-Source (SS) OCT Angiography; Spectral-Domain (SD) OCT Angiography; Fundus Imaging; Axial Length Measurement Device

Conditions: Diabetic Retinopathy; Retinal Vein Occlusion; Hypertension,Essential; Retinal Vascular Disorder

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Exclusion Criteria

  • Both subjects with diseases and controls:
  • Children (age\<18)
  • Pregnant females
  • Developmentally delayed subjects
  • Subjects unable to provide informed consent
  • Inability to cooperate with tests and study instructions
  • Images with motion artifact or signal strength \< 7
  • History of glaucoma
  • History of age-related macular degeneration
  • History of any visually significant eye disease
  • History of proliferative diabetic retinopathy
  • History of any inflammatory disease
  • History of heart disease
  • History of thyroid disease.
  • Additional criteria for controls:
  • History of any type of Diabetes Mellitus
  • History of any type of Hypertension

Recruiting US locations

  • Wilmer Eye Institute

    Baltimore, MD 21287

    Site contact: Ana Collazo Martinez · 410-502-5052 · acollaz5@jhmi.edu

Study contacts (from the official record)

  • Amir H Kashani, MD, PhD · 410-502-2789 · akashan1@jhmi.edu
  • Ana C Martinez, MPH · 410-502-2789 · acollaz5@jhmi.edu
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Optical Coherence Tomography Angiography in Subjects With Retinal… (NCT04505618) | Bored Studies