Pain in Aging Former Athletes, Master's Athletes, and Nonathletes
Marquette University · NCT07502742
Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.
Key facts
- Compensation
- Not posted. Ask the study team before screening.
- Who can join
- Ages 35–65 · All sexes
- Healthy volunteers
- Accepted
- Study type
- Interventional · Not applicable
- Target enrollment
- 90
- US sites recruiting
- 1
- Study start
- March 2, 2026
- Record last updated
- March 31, 2026
Status re-checked against ClinicalTrials.gov within the last 12 hours.
What the study is about
The goal of this clinical trial is to determine how male and female former athletes experience pain and respond to moderate-intensity exercise (strength versus aerobic) compared with both current master's athletes and nonathletes.
The main questions this study aims to address are:
- How do former athletes, master's athletes, and nonathletes experience pain?
- How do different types of moderate-intensity exercise (strength versus aerobic exercise) influence pain in former athletes, master's athletes, and nonathletes?
Participants will complete 3 different testing sessions:
- Baseline testing including assessments of strength, cardiorespiratory fitness, and pain;
- Strength exercise: pain assessments will occur before and after moderate-intensity strength training exercise;
- Aerobic exercise: pain assessments will occur before and after moderate-intensity aerobic exercise.
There will be a washout period of approximately one week or greater between each of the three different testing sessions. The order of conditions (strength versus aerobic exercise) will be randomized (crossover randomized trial design).
Being studied: Moderate-Intensity Strength Exercise Intervention; Moderate-Intensity Aerobic Exercise Intervention
Conditions: Pain; Pain Management; Athlete; Exercise Training; Sports Medicine; Strength Training Effects; Aerobic Exercise; Strength Training; Aging; Quality of Life; Sports
Eligibility criteria
Copied from the official record. The study team makes the final decision at screening.
Show full criteria
Inclusion Criteria (General):
- Age: 35 years through 65 years
- Current master's athlete, former competitive athletes, or non-athlete control (see details below)
- Ability to participate in exercise and exercise testing based on the Physical Activity Readiness Questionnaire (PAR-Q+)
Exclusion Criteria (General):
- Currently pregnant or planning to become pregnant during the study
- Currently taking heart rate lowering medications (e.g., betablockers) that would impact exercise testing
- Contraindications to ice such as Raynaud's, cryoglobulinemia, cold urticaria, and/or impaired circulation or sensation
- Fibromyalgia and/or chronic regional pain syndrome (CRPS)
- Myocardial infarction or pulmonary embolism in the last 12 months, active cancer, a pacemaker, or any additional condition or disease that would preclude the individual from being able to perform the tests safely
Participants will be enrolled into one of the following three mutually exclusive groups according to the following criteria:
- Former Competitive Athlete: Prior participation in competitive sports at the Tier 3 level or above as per McKay et al. (2022): i.e., "national-level representatives who are performing structured and/or periodized training and are developing proficiency in skills required to perform their sport at the highest level; this tier includes individuals participating in Provincial/State or Academy Programs" or higher participation in sport; Not currently participating in any recreational or competitive sports over the last 5 years (Tier 2 or above)
- Master's Athlete: Currently (within the past year) participating in sports at the Tier 2 level or above (i.e., committed to sports-specific training at least 3 times per week with the intent to compete)(McKay et al., 2022)
- Nonathlete Control: No prior participation in sport at the Tier 3 (Highly Trained/National) Level or above and not currently participating in any competitive sports (i.e., Tier 2 or above) (McKay et al., 2022) for at least 5 years
Recruiting US locations
Marquette University
Milwaukee, WI 53233
Site contact: Jacob J Capin, DPT, PhD · 4142887865 · jacob.capin@marquette.edu
Study contacts (from the official record)
- Jacob J Capin, DPT, PhD · 414-288-7865 · jacob.capin@marquette.edu
Similar studies in Wisconsin
All healthy volunteers studies in Wisconsin →- RecruitingHealthy volunteersPhase 1Overnight stay mentioned
A Study to Learn How ASP3082 is Processed in Healthy Men
Astellas Pharma Global Development, Inc.
- Location
- Madison, WI
- Eligibility basics
- Ages 18–65 · Men only
- RecruitingHealthy volunteersPhase 1
A Trial of Lu AH69593 in Healthy Participants
H. Lundbeck A/S
- Location
- Madison, WI
- Eligibility basics
- Ages 18–55
- RecruitingHealthy volunteersPhase 1
Phase I Study to Assess the Safety and Efficacy of OCU200 for Center-Involved Diabetic Macular Edema (DME)
Ocugen
- Location
- La Crosse, WI + 4 other US sites
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteersPhase 1
A Trial to Compare the Pharmacokinetics of Two Presentations of Navenibart in Healthy Participants
Astria Therapeutics, Inc.
- Location
- Madison, WI + 2 other US sites
- Eligibility basics
- Ages 18–55