Perinatal Autism Genetics and Epigenetics Study

Inclusion Criteria

A. Criteria for Pregnant Women:

• Pregnant women in their 1st or 2nd trimester of a singleton pregnancy.
• Age 18 to 50 years
• Currently use a smart phone

B. ASD Group at age 18 to 27 months

• M-CHAT score >= 4 or POSI score >= 3
• Child has subsequently clinically confirmed diagnosis of ASD, based on ADOS/TAP testing and/or other clinical evaluation

C. Developmental Delay (DD) Group at age 18 to 27-months

• Developmental screening score on SWYC in the "at risk" range.
• Child has subsequently clinically confirmed developmental delay on clinical evaluation and/or self-report measure

D. Typically Developing (TD) Group at age 18 to 27 months - None

Exclusion Criteria

A. Criteria for Pregnant Women:

• Non-English speaking mother
• History of severe mental illness in the past year, resulting in inpatient admission

B. All children

• \<35 weeks gestational age at birth
• History of serious neonatal complications requiring NICU admission for one week or more
• Known genetic or syndromic condition (e.g. Down Syndrome, etc.) that impacts learning and brain development
• Hearing impairment

C. ASD Group at age 18 to 27 months

• None

D. Developmental Delay (DD) Group at age 18 to 27 months

• Screen positive for ASD (M-CHAT >= 4 AND POSI >= 3)
• First-degree relative who has been diagnosed with ASD

E. Typically Developing (TD) Group at age 18 to 27 months

• Screen positive for ASD (M-CHAT >= 4 AND POSI >= 3)
• Developmental screening/assessment score in the "at risk" range.
• First-degree relative who has been diagnosed with ASD