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RecruitingAccepts healthy volunteersPhase 2

Pharmaceutically-Enhanced Reinforcement for Reduced Alcohol and Smoking

Washington State University · NCT05181891

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 18+ · All sexes
Healthy volunteers
Accepted
Study type
Interventional · Phase 2
Target enrollment
205
US sites recruiting
1
Study start
July 11, 2022
Record last updated
July 6, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

Using a randomized controlled trial (RCT), the goal of this study is to evaluate the ability of evidence based behavioral treatment (contingency management: CM) to significantly decrease alcohol use and cigarette smoking among treatment-seeking smokers with an alcohol use disorder (AUD) who have initiated pharmacotherapy (varenicline; VC) for smoking cessation.

Being studied: Contingency Management; Non-contingent control

Conditions: Alcohol Use Disorder (AUD); Nicotine Use Disorder

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • 4 or more standard drinks on the same occasion for women (5 or more standard drinks on the same occasion for men) on at least 4 occasions in the prior 30 days
  • Seeking AUD treatment
  • Seeking smoking cessation treatment
  • Aged 18+ years
  • DSM-5 diagnosis of AUD
  • Currently smoking daily according to PhenX Smoking Status (100 or more lifetime cigarettes plus current daily smoking)
  • Ability to read and speak English
  • Ability to provide written informed consent
  • Breath alcohol of 0.00 during informed consent
  • Provision of at least 1 EtG-positive urine test at any time during the induction period and at least one COT-positive urine test at any time during the induction period; and
  • Attended at least 4 of 6 possible visits during the induction period.

Exclusion Criteria

  • Significant risk of dangerous alcohol withdrawal, defined as a history of alcohol detoxification or seizure in the last 12 months and expression of concern by the participant about dangerous withdrawal
  • Currently receiving any pharmacotherapy for alcohol
  • Currently receiving any pharmacotherapy for smoking
  • No suicide attempt in the last 20 years and
  • Any other medical (discernable by initial blood tests) or psychiatric condition that Drs. Layton or Rodin determine would compromise safe participation.

Recruiting US locations

  • Washington State University

    Spokane, WA 99202

    Site contact: Research Coordinator · 509-638-2376 · wsu.appl@wsu.edu

Study contacts (from the official record)

  • Research Coordinator · 509-638-2376 · wsu.appl@wsu.edu
All smoking & vaping studies in Washington →
Pharmaceutically-Enhanced Reinforcement for Reduced Alcohol and… (NCT05181891) | Bored Studies