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Physiology of Long COVID-19 and the Impact of Cardiopulmonary Rehabilitation on Quality-of-Life and Functional Capacity

University of Colorado, Denver · NCT05566483

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 18+ · All sexes
Healthy volunteers
Accepted
Study type
Interventional · Not applicable
Target enrollment
30
US sites recruiting
1
Study start
March 1, 2023
Record last updated
December 4, 2025

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

The primary objectives of this study are to determine whether exercise training is an effective strategy for treatment of Long COVID and characterize the cardiorespiratory and autonomic physiology in these patients to precisely characterize mechanisms contributing to this syndrome.

Being studied: Exercise

Conditions: Post-acute Sequelae of SARS-CoV-2 Infection

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • Adults ≥18 years with documented history of COVID-19 infection and symptoms consistent with Long COVID lasting >12 weeks after diagnosis.

Exclusion Criteria

  • History of cardiovascular/pulmonary disease prior to infection
  • COVID-related myocardial injury such as evidence of myocarditis
  • Deep vein thrombosis/pulmonary embolism following COVID-19 infection
  • Exercise intolerance resulting from conditions that are not related to cardiorespiratory or autonomic factors (e.g. osteoarthritis or other musculoskeletal diseases);
  • Dependency of supplemental oxygen following COVID infection due to cardiovascular and/or pulmonary complications following acute COVID infection

Recruiting US locations

  • University of Colorado Hospital

    Aurora, CO 80045

    Site contact: William K Cornwell, III, MD

Study contacts (from the official record)

  • William K Cornwell, III, MD · 303-724-2085 · william.cornwell@cuanschutz.edu
All healthy volunteers studies in Colorado →
Physiology of Long COVID-19 and the Impact of Cardiopulmonary… (NCT05566483) | Bored Studies