Pilot Study of the YES-CAN! Program to Prevent Youth Nicotine Vaping
University of Colorado, Denver · with National Institute on Drug Abuse (NIDA) · NCT07009509
Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.
Key facts
- Compensation
- Not posted. Ask the study team before screening.
- Who can join
- Ages 9+ · All sexes
- Healthy volunteers
- Accepted
- Study type
- Interventional · Not applicable
- Target enrollment
- 1166
- US sites recruiting
- 1
- Study start
- August 15, 2024
- Record last updated
- July 15, 2025
Status re-checked against ClinicalTrials.gov within the last 12 hours.
What the study is about
The goal of this pilot study is to determine the feasibility of a randomized trial of the YES-CAN! (Youth Engaged Strategies to Change Adolescent Norms) program to prevent nicotine vaping among adolescents. The program integrates the following evidence-based strategies: youth-adult collaboration; youth-developed narrative videos to convey health messages; peer leaders as change agents; and sustained implementation to change the normative environment. Two middle/high school communities will receive the YES-CAN! intervention. In each school community, a trained teacher will deliver a credit-earning middle or high school class to 25-30 middle or high school students, who will produce 6-8 short videos intended to increase refusal skills; promote stress management and positive coping; change social norms; prevent vaping initiation; and promote vaping cessation among current users. Videos will use a narrative approach and integrate known determinants of vaping. Middle or high school students will collaborate with the teacher and researchers to develop discussion guides and skills-building activities based on best practices for substance use prevention. In 6-8 sessions, middle or high school students will deliver their videos to all students in the associated middle school. A text messaging or other media component will reinforce and boost the effectiveness of the classroom sessions.
Aims for this pilot/feasibility study are
- To determine the feasibility and acceptability of implementing the YES-CAN! program
- To determine the feasibility and acceptability of the research protocols that will be used in a future efficacy trial
Being studied: YES-CAN! program
Conditions: Nicotine Vaping
Eligibility criteria
Copied from the official record. The study team makes the final decision at screening.
Show full criteria
Inclusion Criteria
- Children enrolled in middle school grades 6-8 and high school grades 9-12 (age approximately 10-13 and 14-17); adults (over age 18) involved in educational system
Exclusion Criteria
- Not able to read and write in English or Spanish
Recruiting US locations
University of Colorado Anschutz Medical Campus
Aurora, CO 80045
Site contact: Lori A Crane, PhD, MPH · 303-724-4385 · lori.crane@cuanschutz.edu
Study contacts (from the official record)
- Lori A Crane, PhD, MPH · 3037244385 · lori.crane@cuanschutz.edu
- Nancy L Asdigian, PhD · 7203243748 · nancy.asdigian@cuanschutz.edu
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