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Pilot Study of the YES-CAN! Program to Prevent Youth Nicotine Vaping

University of Colorado, Denver · with National Institute on Drug Abuse (NIDA) · NCT07009509

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 9+ · All sexes
Healthy volunteers
Accepted
Study type
Interventional · Not applicable
Target enrollment
1166
US sites recruiting
1
Study start
August 15, 2024
Record last updated
July 15, 2025

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

The goal of this pilot study is to determine the feasibility of a randomized trial of the YES-CAN! (Youth Engaged Strategies to Change Adolescent Norms) program to prevent nicotine vaping among adolescents. The program integrates the following evidence-based strategies: youth-adult collaboration; youth-developed narrative videos to convey health messages; peer leaders as change agents; and sustained implementation to change the normative environment. Two middle/high school communities will receive the YES-CAN! intervention. In each school community, a trained teacher will deliver a credit-earning middle or high school class to 25-30 middle or high school students, who will produce 6-8 short videos intended to increase refusal skills; promote stress management and positive coping; change social norms; prevent vaping initiation; and promote vaping cessation among current users. Videos will use a narrative approach and integrate known determinants of vaping. Middle or high school students will collaborate with the teacher and researchers to develop discussion guides and skills-building activities based on best practices for substance use prevention. In 6-8 sessions, middle or high school students will deliver their videos to all students in the associated middle school. A text messaging or other media component will reinforce and boost the effectiveness of the classroom sessions.

Aims for this pilot/feasibility study are

  • To determine the feasibility and acceptability of implementing the YES-CAN! program
  • To determine the feasibility and acceptability of the research protocols that will be used in a future efficacy trial

Being studied: YES-CAN! program

Conditions: Nicotine Vaping

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • Children enrolled in middle school grades 6-8 and high school grades 9-12 (age approximately 10-13 and 14-17); adults (over age 18) involved in educational system

Exclusion Criteria

  • Not able to read and write in English or Spanish

Recruiting US locations

  • University of Colorado Anschutz Medical Campus

    Aurora, CO 80045

    Site contact: Lori A Crane, PhD, MPH · 303-724-4385 · lori.crane@cuanschutz.edu

Study contacts (from the official record)

  • Lori A Crane, PhD, MPH · 3037244385 · lori.crane@cuanschutz.edu
  • Nancy L Asdigian, PhD · 7203243748 · nancy.asdigian@cuanschutz.edu
Pilot Study of the YES-CAN! Program to Prevent Youth Nicotine Vaping (NCT07009509) | Bored Studies