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Precision Analytic Research Methods in OCD

Icahn School of Medicine at Mount Sinai · with National Institute of Mental Health (NIMH) · NCT07011901

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 18–55 · All sexes
Healthy volunteers
Accepted
Study type
Interventional · Not applicable
Target enrollment
100
US sites recruiting
1
Study start
July 9, 2025
Record last updated
October 23, 2025

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

Psychiatric disorders characterized by compulsivity, such as obsessive-compulsive disorder (OCD), result in considerable functional impairment and many individuals do not respond to gold-standard treatments. Compulsivity has long been thought to occur due to exaggerated habits and reduced goal-directed control, although more recently, this conceptualization of compulsivity as an imbalance of two cognitive systems has been challenged as overly narrow. This study will recruit 100 individuals (50 adults diagnosed with OCD, 50 healthy controls) and leverage the measurement precision offered by theory-driven computational modeling in combination with electroencephalogram (EEG) to go beyond this binary theory of compulsivity, revealing how more complex interactions of neurocognitive subcomponents contribute to compulsivity-information that could ultimately lead to improved treatment personalization and clinical outcomes.

Being studied: Exposure and Response Prevention

Conditions: Obsessive Compulsive Disorder

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

Participants must be

  • between the ages 18-55 years old
  • English-speaking
  • right-handed
  • able to provide consent

Exclusion Criteria

Individuals diagnosed with OCD will be excluded if:

  • they meet diagnostic criteria for certain other psychiatric disorders
  • are taking psychiatric medication or have received behavioral treatment for OCD within a certain timeframe
  • if it is unsafe for them to participate in research

Healthy control participants will be excluded if:

  • they have a current psychiatric disorder
  • a lifetime history of certain psychiatric disorders
  • are taking psychiatric medication or have in the past
  • have a parent or sibling who has been diagnosed with OCD
  • if it is unsafe for them to participate in research

Recruiting US locations

  • Icahn School of Medicine at Mount Sinai

    New York, NY 10029

    Site contact: Amy Rapp

Study contacts (from the official record)

  • Amy Rapp, Ph.D. · 212-241-5288 · OCDResearch@mssm.edu
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Precision Analytic Research Methods in OCD (NCT07011901) | Bored Studies