Preop Laxatives in Robotic Urologic Surgery
Chad R. Tracy · NCT05805436
Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.
Key facts
- Compensation
- Not posted. Ask the study team before screening.
- Who can join
- Ages 30–100 · All sexes
- Healthy volunteers
- Accepted
- Study type
- Interventional · Phase 4
- Target enrollment
- 240
- US sites recruiting
- 1
- Study start
- June 1, 2023
- Record last updated
- May 30, 2025
Status re-checked against ClinicalTrials.gov within the last 12 hours.
What the study is about
Minimally-invasive surgery, either laparoscopic or robotic, is commonly used in urology. Several urologic procedures including prostatectomy, radical nephrectomy, and partial nephrectomy are now commonly performed robotically. Patients undergoing these procedures often have delayed return of bowel function and persistent gastrointestinal symptoms including nausea/vomiting, abdominal distension, and bloating for several days to weeks after surgery. Postoperative stool softeners and laxatives are routinely used in an effort to minimize these symptoms, with varying degrees of success. The aim of this study will be to evaluate whether the use of a preoperative osmotic laxative will be beneficial in improving recovery of bowel function and alleviating postoperative gastrointestinal complaints in patients undergoing these procedures. Patients will be randomized to either receive or not receive three days of polyethylene glycol (PEG, also known as MiraLAX) on the three days before surgery. Patients in both groups will receive the same postoperative bowel regimen including scheduled PEG both in the hospital and upon discharge until first bowel movement. Patients will be given a questionnaire and diary to record their postoperative gastrointestinal symptoms and time to first bowel movement. These questionnaires and diaries will then be analyzed to determine differences in time to first bowel movement and gastrointestinal complaints during their recovery from surgery.
Being studied: Polyethylene Glycol 3350
Conditions: Prostate Cancer; Kidney Cancer; Constipation
Eligibility criteria
Copied from the official record. The study team makes the final decision at screening.
Show full criteria
Inclusion criteria
-Patients 30 years or older undergoing robotic-assisted laparoscopic radical prostatectomy, transperitoneal radical nephrectomy, or transperitoneal partial nephrectomy
Exclusion criteria
- Patients under 30 years old
- Patients with a contraindication to receiving polyethylene glycol or other forms of laxatives
- People who regularly take Miralax
- Patients undergoing retroperitoneal radical or partial nephrectomy
- Patients with severe ulcerative colitis or Crohn's disease
- Patients with intestinal diversions (colostomy, ileostomy)
- Patients with prior abdominal or pelvic radiation
- Patients who will not follow up with UIHC postoperatively
- Patients who are incarcerated
Recruiting US locations
University of Iowa Hospitals & Clinics
Iowa City, IA 52242
Site contact: Chad Tracy, MD
Study contacts (from the official record)
- Chad Tracy, MD · +1 319 335 8056 · chad-tracy@uiowa.edu
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