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Prospective Evaluation of Pathways for Preterm Birth

John O'Brien, MD · NCT05246579

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 18–45 · Women only
Healthy volunteers
Accepted
Study type
Observational
Target enrollment
240
US sites recruiting
1
Study start
February 4, 2022
Record last updated
August 4, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

This is a single center, prospective cohort study of pregnant patients at high risk for spontaneous preterm birth: patient's with history of spontaneous preterm birth, patient's with a short cervix and patient's symptomatic for preterm birth will be included. A control cohort of nulliparous patients without a short cervix will be recruited to provide baseline data. Plan to enroll 240 patients identified through our ultrasound unit with goal of 60 patients in each group.

Conditions: Preterm Birth; Cervix; Pregnancy

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • Maternal age from 18 to 45 years of age.
  • Singleton gestation.

Exclusion Criteria

  • Treatment with vaginal progesterone or intramuscular progestogen within the previous 4 weeks.
  • History of congestive heart failure, chronic renal failure, or uncontrolled diabetes mellitus, or diabetes mellitus with evidence of end organ dysfunction secondary to vascular disease.
  • Current pregnancy with a major fetal anomaly or known chromosomal abnormality.
  • The subject has a marked uterine anatomic malformation that may alter pregnancy duration such as a septated uterus, unicornuate uterus, or uterine didelphys.
  • The subject is considered not capable or unwilling to undergo study procedures and requirements.
  • The subject is symptomatic with vaginal bleeding at enrollment visit.

Recruiting US locations

  • University of Kentucky

    Lexington, KY 40506

    Site contact: Cynthia Cockerham · ctcock2@uky.edu

Study contacts (from the official record)

  • Cynthia Cockerham · 859-629-2015 · cynthia.cockerham@uky.edu
All pregnancy studies in Kentucky →
Prospective Evaluation of Pathways for Preterm Birth (NCT05246579) | Bored Studies