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Quantifying Motor Network Dynamics to Predict and Enhance Outcomes in Pediatric Dystonia

Children's Hospital Medical Center, Cincinnati · with National Institute of Neurological Disorders and Stroke (NINDS) · NCT07325175

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 6–21 · All sexes
Healthy volunteers
Accepted
Study type
Interventional · Not applicable
Target enrollment
75
US sites recruiting
1
Study start
September 1, 2026
Record last updated
October 20, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

The goal of this study is to understand the development and progression of childhood dystonia, a movement disorder, in children. The main questions it aims to answer are:

How does the activity of the neural network evolve in children with dystonia in the context of motor development? What are the effects of chronic and active stimulation on cortical and subcortical motor network function in children with deep brain stimulation (DBS)?

Participants will

  • Undergo noninvasive electrophysiological measurements (EEG, EMG) to quantify neural network activity. They will be tested at rest and during a simple motor reaction task.
  • Children with DBS will be assessed in the on and off DBS state to assess effects of chronic and active changes in motor network function.

Being studied: DBS

Conditions: Dystonia; Pediatric; Deep Brain Stimulation; Motor Development

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • For dystonia subjects:
  • Dx of dystonia (with and without DBS)
  • willingness and ability to complete study protocols.
  • For Typically Developing Controls:
  • normal developmental milestones
  • absence of any neuropsychiatric disorder
  • no significant medical condition.

Exclusion Criteria

  • history of epilepsy
  • presence of implanted medical devices (except DBS in dystonia subjects)
  • lack of cognitive or physical ability to complete study protocol.

Recruiting US locations

  • Cincinnati Children's Hospital Medical Center

    Cincinnati, OH 45229

    Site contact: Karlee Migneault · 513-636-4200 · karlee.migneault@cchmc.org

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Quantifying Motor Network Dynamics to Predict and Enhance Outcomes… (NCT07325175) | Bored Studies