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ReadMap: Reading in Stroke Alexia and Typical Aging

Georgetown University · with MedStar National Rehabilitation Network, National Institute on Deafness and Other Communication Disorders (NIDCD) · NCT06700005

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 18+ · All sexes
Healthy volunteers
Accepted
Study type
Observational
Target enrollment
300
US sites recruiting
1
Study start
January 12, 2023
Record last updated
November 21, 2024

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

Loss of reading ability due to stroke, called alexia, likely affects over a million Americans at any given time and causes difficulty performing many daily life functions, such as paying bills, using email/text, reading for pleasure, and reading signs in the community. Understanding the brain and cognitive basis of alexia could improve diagnosis and treatment of this important problem. In this study, the investigators will perform a large-scale behavioral and brain imaging study of stroke survivors and typical older adults to improve our understanding of the brain and cognitive basis of reading in both of these groups.

Participants will complete a battery of tests of reading, speech, language, and thinking abilities. In addition, some participants will complete an MRI. Sessions will be completed across approximately 2-6 weeks, but may be extended depending on participants' schedules and availability. Some participants will be invited to repeat these procedures once or twice in approximately 3-12 months to monitor for changes in reading abilities and MRI measurements over time.

Conditions: Aphasia; Stroke; Alexia

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion criteria

Stroke Survivors

  • Age >= 18
  • Learned English at 8 years or younger
  • Brain injury resulting from stroke

Controls

  • Age >= 18
  • Learned English at 8 years or younger

Exclusion criteria for all groups

  • History of other brain disorder that could interfere with our ability to interpret results (e.g., Multiple sclerosis, dementia, head injury causing loss of consciousness)
  • Severe psychiatric condition that would interfere with participation in the study
  • History of diagnosed learning disorder
  • Hearing or vision loss that interferes with performance on behavioral tests even after correction with glasses/hearing aids.
  • Inability to follow study procedures despite maximal support

Additional exclusion criteria for MRIs

  • Presence of metal in the body that is incompatible with MRI
  • Pregnancy
  • Claustrophobia

Recruiting US locations

  • Georgetown University Medical Center

    Washington D.C., DC 20057

    Site contact: Alycia Laks, MS, CCC-SLP · 202-687-5205 · crlab@georgetown.edu

Study contacts (from the official record)

  • Alycia Laks, MS, CCC-SLP · 202-687-5205 · crlab@georgetown.edu
All neurology studies in District of Columbia →
ReadMap: Reading in Stroke Alexia and Typical Aging (NCT06700005) | Bored Studies