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RecruitingAccepts healthy volunteersEarly Phase 1

Researching Economical Adjuvants to Cancer Therapy

Florida State University · NCT07305259

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 18–45 · All sexes
Healthy volunteers
Accepted
Study type
Interventional · Early Phase 1
Target enrollment
60
US sites recruiting
1
Study start
November 12, 2025
Record last updated
December 26, 2025

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

The goal of this clinical trial is to learn if beta-glucan (a dietary fiber) improves the function of the immune system in adults. It will also tell the investigators if combining beta-glucan with single bouts of exercise provides additional benefit. The main questions it aims to answer are:

  • Does beta-glucan change the ability of immune cells to recognize cancer cells?
  • Does exercise change the type of immune cells in the blood? Researchers will compare beta-glucan to a placebo (a look-alike substance with no effect) to see if beta-glucan could improve immune function against cancer.

Participants will

  • Take beta-glucan or a placebo daily for 4 weeks.
  • Visit the laboratory for three exercise tests.
  • Provide blood samples so researchers can study immune system cells.

Being studied: Beta-glucan; Placebo

Conditions: Healthy Participants

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • Physically fit enough to engage in maximal exercise.

Exclusion Criteria

  • BMI > 40 kg/m2
  • Stage 2 hypertension (140/90 mmHg)
  • Type I or II diabetes
  • Autoimmune diseases
  • Overt cardiovascular, respiratory, or neurological disease (e.g., previous heart attack, pacemaker, heart failure, asthma)
  • Hormone replacement therapy (e.g., androgens, estrogens)
  • Daily medication usage that may affect immune function (e.g., beta blockers, NSAIDs, corticosteroids, allergy medications)
  • Current antibiotic use
  • Heavy alcohol usage (>2 drinks per day)
  • Tobacco use within the last 6 months
  • Adults unable to consent
  • Individuals who are not yet adults (infants, children, teenagers)
  • Self-reported pregnancy
  • Prisoners

Recruiting US locations

  • Institute of Sports Sciences and Medicine

    Tallahassee, FL 32306

    Site contact: Kyle A Smith, PhD, RD · 8506451016 · k.smith@fsu.edu

Study contacts (from the official record)

  • Kyle A Smith, PhD, RD · 850-644-1016 · k.smith@fsu.edu
All healthy volunteers studies in Florida →
Researching Economical Adjuvants to Cancer Therapy (NCT07305259) | Bored Studies