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RecruitingAccepts healthy volunteersPhase 4

Risk of Acute Complications With Rocuronium vs Cisatracurium in Patients With Chronic Kidney Disease

The University of Texas Medical Branch, Galveston · NCT07203287

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 18–80 · All sexes
Healthy volunteers
Accepted
Study type
Interventional · Phase 4
Target enrollment
490
US sites recruiting
1
Study start
August 26, 2025
Record last updated
October 20, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

The purpose of the study is to determine which combination of neuromuscular blocking agent and reversal agent is safer to use during anesthesia for patients with chronic kidney disease. The main question it aims to answer is

"The use of Cisatracurium with neostigmine leads to less post-operative pulmonary complications than Rocuronium with sugammadex."

Being studied: Rocuronium; Cisatracurium; Sugammadex; Neostigmine

Conditions: Post Operative Pulmonary Complications; Neuromuscular Blockade; General Anesthesia

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • The subject is able and willing to provide and sign informed consent
  • The subject must be between 18 and 80 years of age
  • The subject should have chronic kidney disease as defined by glomerular filtration rate
  • The surgery must require general anesthesia with endotracheal intubation and neuromuscular blockade

Exclusion Criteria

  • Any patient under the age of 18
  • Any patient over the age of 80
  • Any patient with end stage renal disease
  • Any patient requiring dialysis
  • Patients presenting for Renal Transplantation
  • Pregnant Female
  • Any patient in the correctional system
  • Urgent or Emergent procedure
  • The surgery requires intubation post-operatively
  • Documented allergy to Rocuronium, Sugammadex, Cisatracurium or Neostigmine

Recruiting US locations

  • University of Texas Medical Branch

    Galveston, TX 77554

    Site contact: Michael Kinsky, MD · 409-772-1011 · mkinsky@utmb.edu

Study contacts (from the official record)

  • Michael Kinsky, MD · 409-772-1011 · mkinsky@utmb.edu
Risk of Acute Complications With Rocuronium vs Cisatracurium in… (NCT07203287) | Bored Studies