Safety and Feasibility of an ExoNET for Supination Assistance for Stroke Survivors
Shirley Ryan AbilityLab · NCT06655636
Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.
Key facts
- Compensation
- Not posted. Ask the study team before screening.
- Who can join
- Ages 40–70 · All sexes
- Healthy volunteers
- Accepted
- Study type
- Interventional · Not applicable
- Target enrollment
- 30
- US sites recruiting
- 1
- Study start
- December 4, 2024
- Record last updated
- January 9, 2025
Status re-checked against ClinicalTrials.gov within the last 12 hours.
What the study is about
The purpose of this study is to evaluate the safety, feasibility, and efficacy of an exoskeletal network of passive, multi-joint springs for forearm supination. Also known as the forearm ExoNET, the device is a passive, robotic device that will properly assist forearm supination in the post-stroke adult population.
Being studied: Device tuned to Assistance; Device tuned to Sham (Slack Springs); Device tuned to Anti-Assistance
Conditions: Stroke; Cerebral Vascular Accident
Eligibility criteria
Copied from the official record. The study team makes the final decision at screening.
Show full criteria
Inclusion Criteria
- Between the ages of 40-70 (to reduce confounding effects of aging on muscle, movement accuracy and proprioception)
- Have sustained a single, unilateral stroke at least 8 months prior to enrollment
- Severe to moderate upper extremity impairment (ARAT score 0-30)
- Ability to move their elbow and wrist when supported against gravity
- Cortical stroke with hemiparesis, tactile sensation
- Available medical records about lesion locations indicating the stroke was caused by a middle cerebral artery ischemic infarct
Exclusion Criteria
- Bilateral paresis
- Diffuse/multiple lesion sites or multiple stroke events
- Hemispatial neglect or visual field cut that prevent visual feedback
- Shoulder pain and/or articular rigidity on the upper limb joint
- Severe sensory deficits indicated by the Two-Point Discrimination Test
- Botox injection to the affected upper extremity within the previous 4 months
- Aphasia, cognitive impairment, or affective dysfunction that would influence the ability to consent, perform the experiment, or follow commands
- Concurrent participation in upper extremity rehabilitation either as part of a research intervention protocol or a prescribed therapy
- Other neurological issues
- Meet any of the contraindications to Delsys Trigno Sensors:
- Implanted with electronic devices of any kind, including cardiac pace-makers or similar assistive devices, electronic induction pumps, and implanted stimulators
- Irritated skin or open wounds
- Silver allergy
Recruiting US locations
Shirley Ryan AbilityLab
Chicago, IL 60610
Site contact: Courtney Celian, OTR/L · 312-238-1560 · ccelian@sralab.org
Study contacts (from the official record)
- Valentino I Wilson · 630-398-2355 · viwilso2@uic.edu
- Courtney Celian, MSOT · 312-238-1560 · ccelian@sralab.org
Similar studies in Illinois
All neurology studies in Illinois →- RecruitingHealthy volunteersEarly Phase 1
Effect of Neural Constraints on Movement in Stroke
Northwestern University
- Location
- Chicago, IL
- Eligibility basics
- Ages 18–80
- RecruitingHealthy volunteersEarly Phase 1
R01.Aim 2.Study 1: IsoReach
Shirley Ryan AbilityLab
- Location
- Chicago, IL
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteers
Development of a Home Test for Measuring Blood P-tau217 in Alzheimer's Disease Using the Tasso Lancet Device
Neurogen Biomarking LLC
- Location
- Chicago, IL
- Eligibility basics
- Ages 40–90
- RecruitingHealthy volunteers
Development of a Database to Investigate Digital and Blood-Based Biomarkers and Their Relationship to Tau and Amyloid PET Imaging in Older Participants Who Are Cognitively Normal (CN), Have Mild Cognitive Impairment…
GAP Innovations, PBC
- Location
- Chicago, IL + 18 other US sites
- Eligibility basics
- Ages 60–90