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RecruitingAccepts healthy volunteersPhase 1

Single and Multiple Dose Study to Evaluate Safety and Pharmacokinetics of BMS-986533 in Healthy Participants and Assessments of Food and pH Effects on Relative Bioavailability, and Drug-Drug Interaction Potential in Healthy Participants

Bristol-Myers Squibb · NCT07629999

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 18–55 · All sexes
Healthy volunteers
Accepted
Study type
Interventional · Phase 1
Target enrollment
136
US sites recruiting
1
Study start
July 13, 2026
Record last updated
July 24, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

The purpose of this study is to evaluate the safety and pharmacokinetics of BMS-986533 in healthy participants receiving single and multiple doses, to assess food and pH effects on the relative bioavailability of BMS-986533, and the P-gp and BCRP-mediated drug-drug interaction potential of the study drug

Being studied: BMS-986533; Famotidine; Placebo; Dabigatran Etexilate; Rosuvastatin

Conditions: Healthy Volunteers

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • Participants must have a body mass index (BMI) of 18 to 32.44 kg/m2, inclusive, and total body weight ≥ 50 kg.
  • Female (as assigned at birth) participants who are not of childbearing potential must have documented proof of reproductive status.
  • A male (as assigned at birth) who is sexually active with IOCBP must agree to follow instructions for method(s) of contraception as described and included in the ICF.

Exclusion Criteria

  • Participants must not have presence or history of any clinically relevant abnormality, condition, or disease of renal, hepatic, hematologic, GI, endocrine, pulmonary, neurologic, or immunologic (including history of angioedema or hypersensitivity reactions to medication).
  • Participants must not have current or recent (within 3 months of study intervention administration) clinically significant GI disease.
  • Participants must not have any major surgery within 3 months of study intervention administration.
  • Participants must not have Any surgical or medical intervention that could possibly affect ADME of study intervention (eg, bariatric surgery, GI surgery).
  • Other protocol defined inclusion/exclusion criteria applies.

Recruiting US locations

  • Celerion Coorporate Office Nebraska

    Lincoln, NE 68502

    Site contact: Allen Hunt, Site 0001

Study contacts (from the official record)

  • BMS Clinical Trials Contact Center www.BMSClinicalTrials.com · 855-907-3286 · Clinical.Trials@bms.com
  • First line of the email MUST contain NCT # and Site #.
Single and Multiple Dose Study to Evaluate Safety and… (NCT07629999) | Bored Studies