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Skeletal Muscle Energetics and Fatiguability in Older Individuals

Johns Hopkins University · with National Institute on Aging (NIA) · NCT04142047

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 60–90 · All sexes
Healthy volunteers
Accepted
Study type
Observational
Target enrollment
200
US sites recruiting
1
Study start
September 5, 2019
Record last updated
June 8, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

The investigators are studying whether metabolic abnormalities in calf (leg) muscle in older people with and others without HIV are associated with decreased abilities to exercise.

Conditions: HIV; HIV Infections

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • Participants who are >= 60 years of age
  • HIV serostatus positive participants on stable antiretroviral therapy (ART) (no regimen change in last month) with undetectable HIV viral load (\<100 copies).
  • HIV serostatus negative participants

Exclusion Criteria

  • Unable to understand the risks, benefits, and alternatives of participation and give meaningful consent
  • Contraindications to MRI
  • Significant cardiovascular, pulmonary or musculoskeletal or orthopedic disease that significantly limits exercise capacity
  • Significant lower extremity peripheral vascular disease.
  • Weight greater than 350 lbs
  • Cognitive or speech impairments that would limit completion of questionnaires or fatigue reporting.

Recruiting US locations

  • Johns Hopkins Hospital

    Baltimore, MD 21287

    Site contact: Tricia Steinberg, MSN · 443-287-3469 · asteinb3@jhmi.edu

Study contacts (from the official record)

  • Maria Esteban, RN, BSN · 410-955-1160 · mesteba1@jh.edu
  • Tricia Steinberg, RN, MSN · 443-287-3469 · asteinb3@jhmi.edu
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Skeletal Muscle Energetics and Fatiguability in Older Individuals (NCT04142047) | Bored Studies