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Sleep Restriction and Parental History of Hypertension

Mayo Clinic · with National Heart, Lung, and Blood Institute (NHLBI) · NCT06482814

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 18–35 · All sexes
Healthy volunteers
Accepted
Study type
Interventional · Not applicable
Target enrollment
44
US sites recruiting
1
Study start
February 20, 2025
Record last updated
August 13, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

The purpose of this study is to research the effects of partial sleep deprivation (sleep restriction) in a group of individuals whose parents have high blood pressure compared to a group of individuals whose parents have normal blood pressure.

Being studied: Partial sleep deprivation (sleep restriction); Normal sleep

Conditions: Hypertension

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • Healthy adults aged 18-35 years
  • Absence of any significant medical or psychiatric disease (as per the investigators' judgment)
  • Nonsmoker
  • Nonpregnant
  • History of normal sleep duration (reported average sleep duration between 7-9 hours/night and no habitual napping)
  • Hypertension status information available for both biological parents
  • Ability to understand study procedures and to comply with them for the entire length of the study
  • Ability to understand English and provide informed consent

Exclusion Criteria

  • Age \<18 or >35 years
  • Body mass index \<18.5 or ≥30 kg/m2
  • Pregnant or lactating
  • Unable to determine history of HTN in participant's biological parents or subject being adopted
  • Use of tobacco, vaping, marijuana products or other drugs
  • Excessive caffeine consumption (>400 mg/day)
  • Excessive alcohol consumption (>7 drinks/week for women, >14 drinks/week for men)
  • Office SBP/DBP ≥130/80 mmHg
  • Daytime ambulatory SBP/DBP ≥130/80 mmHg
  • Fasting glucose ≥126 mg/dl
  • Glomerular filtration rate \<60 mL/min/BSA
  • History of significant medical or psychiatric disorders (as per the investigators' judgment)
  • Regular use of prescription medications other than contraceptives
  • Use of melatonin supplements or any other over-the-counter sleep aid
  • Moderate-to-severe sleep disordered breathing (apnea/hypopnea index, AHI ≥15) or mild sleep disordered breathing (AHI 5-15) with daytime sleepiness (Epworth Sleepiness Scale >10)
  • Moderate-to-severe insomnia (Insomnia Severity Index >14)
  • Restless leg syndrome (as per the Cambridge-Hopkins questionnaire)
  • Excessive daytime sleepiness (Epworth Sleepiness Scale >15)
  • Extreme chronotype (Morningness-Eveningness Questionnaire >69 or \<31)
  • Night shift work
  • Ongoing participation in other research studies (as per the investigators' judgment)
  • Any other medical, geographic, or social factor making study participation impractical
  • Not English-speaking and/or inability to provide informed consent
  • Exclusionary for blood draws: hemoglobin \<11.6 g/dL in women / \<13.2 g/dL in men; participants with measured hemoglobin levels below these thresholds will be allowed to continue participate in study tests and procedures not involving blood draws.

Recruiting US locations

  • Mayo Clinic in Rochester

    Rochester, MN 55905

    Site contact: Naima Covassin

Study contacts (from the official record)

  • Sabah Munir · (507)255-0151 · Munir.Sabah@mayo.edu
All sleep studies in Minnesota →
Sleep Restriction and Parental History of Hypertension (NCT06482814) | Bored Studies