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Sodium vs Potassium Education to Improve Vascular Health

Florida State University · with United States Department of Agriculture (USDA) · NCT07221448

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 18–45 · All sexes
Healthy volunteers
Accepted
Study type
Interventional · Not applicable
Target enrollment
32
US sites recruiting
1
Study start
April 20, 2026
Record last updated
April 23, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

The goal of this clinical trial is to determine if a self-selected high potassium diet is easier to achieve and more effective at improving vascular health than a low sodium diet in generally healthy young adults who typically consume more than the recommended amount of sodium. The main questions it aims to answer are:

  • Is it easier for young adults to increase their potassium intake, rather than reduce their sodium intake?
  • Is a self-selected high potassium diet better at improving vascular health compared to a self-selected low sodium diet?

Researchers will compare the effectiveness of an education-based intervention centered only on increasing dietary potassium intake against an education-based intervention centered only on reducing dietary sodium intake.

Participants will be randomly assigned to receive comprehensive dietary education on adopting either a high-potassium diet or a low-sodium diet.

Education will be delivered in four weekly one-on-one sessions. Following the four-week education period, participants will be encouraged to change their diet based on what they have learned. Measures of dietary compliance (urine samples and diet records) and cardiovascular health (blood pressure, endothelial function) will be assessed at two, four, and six months post-education.

Being studied: High potassium dietary education/counseling; Low sodium dietary education/counseling

Conditions: Healthy

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • Willing and able to attend in-person laboratory visits
  • Usual sodium intake ≥3,000 mg/d for females and ≥4,000 mg/d for males
  • Usual potassium intake ≤2,500 mg/d in females and ≤3,000 mg/d in males

Exclusion Criteria

  • BMI ≥35 kg/m2
  • Seated blood pressure ≥130/80 mmHg
  • Current diagnosis or history of diabetes, renal disease, cancer, cardiovascular disease, or major cardiovascular event (e.g. heart attack or stroke)
  • Current or recent use of a diuretic (within the past 6 months)
  • Elevated blood lipids (LDL cholesterol ≥190 mg/dL)
  • Elevated serum potassium level (>5.1 mmol/L)
  • Elevated BUN (>22 mg/dL)
  • Elevated creatinine (>1.2 mg/dL)
  • Low eGFR (\<90 mL/min/1.73 m²)
  • Current or recent use of tobacco, nicotine, or illicit drugs
  • Radical hysterectomy or oophorectomy (females)*
  • Pregnant or lactating
  • Following a weight-loss diet, or intending to gain or lose weight during the study period

Recruiting US locations

  • Florida State University

    Tallahassee, FL 32304

    Site contact: Andrea Lobene, PhD, RD, LD · 850-644-1829 · alobene@fsu.edu

Study contacts (from the official record)

  • Andrea Lobene, PhD, RD, LD · 850-644-1829 · alobene@fsu.edu
  • FSU Ann's College · 850-644-6685
All heart & blood pressure studies in Florida →
Sodium vs Potassium Education to Improve Vascular Health (NCT07221448) | Bored Studies